Department of Ultrasonography, The Affiliated Infectious Diseases Hospital of Soochow University, 2 Xier Road, Suzhou, 215101, China.
Department of Ultrasound, The Affiliated Suzhou Hospital of Nanjing Medical University, No. 1 Lijiang Road, Suzhou, 215163, China.
Cancer Imaging. 2019 Mar 20;19(1):16. doi: 10.1186/s40644-019-0204-x.
Over the past ten years, more papillary thyroid microcarcinoma (PTMC) has been diagnosed more frequently due to the development of imaging technology, and the incidence of PTMC has increased significantly. Ultrasound-guided percutaneous laser ablation (PLA) is mainly used for benign thyroid nodules, and few studies have been published on the use of PLA for PTMC. In the present study, a retrospective analysis was performed to explore the efficacy of PLA for PTMC.
A total of 37 patients with PTMC who underwent PLA were included in this study. Measurement of the lesion volume and serum thyroid hormone levels and clinical evaluation were performed at 1, 3, 6, and 12 months and every 6 months thereafter.
We found that all patients were successfully treated with PLA without serious complications. At the last follow-up visit, 12/37 (32.4%) primary lesions had disappeared, and 24/37 (64.9%) remained as cicatricial hyperplasia. One patient (2.7%) had cervical lymph node metastasis at 24 months post-operatively and underwent open surgery.
Our initial studies suggest that ultrasound-guided PLA is a safe and effective treatment for PTMC.
过去十年间，随着影像技术的发展，更多的甲状腺微小乳头状癌（PTMC）被诊断出来，PTMC 的发病率显著升高。超声引导下经皮激光消融术（PLA）主要用于治疗良性甲状腺结节，目前仅有少数研究报道了 PLA 治疗 PTMC 的应用。本研究对 PLA 治疗 PTMC 的疗效进行了回顾性分析。
共纳入 37 例接受 PLA 治疗的 PTMC 患者。在 1、3、6 和 12 个月及此后每 6 个月进行病变体积和血清甲状腺激素水平测量及临床评估。
所有患者均成功接受 PLA 治疗，无严重并发症。末次随访时，37 例患者中 12 例（32.4%）原发灶完全消失，24 例（64.9%）遗留瘢痕样增生。1 例患者（2.7%）术后 24 个月出现颈淋巴结转移，行开放手术。
初步研究表明，超声引导下 PLA 治疗 PTMC 安全有效。
