Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, 88 Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, Korea.
Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, 86 Asanbyeongwon-Gil, Songpa-gu, Seoul, 05505, Korea.
Curr Oncol Rep. 2022 Aug;24(8):1045-1052. doi: 10.1007/s11912-022-01268-2. Epub 2022 Apr 6.
Thermal ablation presents a therapeutic option other than active surveillance and immediate surgery for patients with low-risk papillary thyroid microcarcinomas (PTMC). Here, we have reviewed the current oncologic outcome of thermal ablation in PTMC cases and compared it with active surveillance and surgery.
Thermal ablation in PTMC cases revealed no tumor progression for pooled 5-year follow-up data. This oncologic outcome of thermal ablation was comparable to that of immediate surgery with less morbidity. Additionally, no patient who underwent thermal ablation received delayed surgery during the follow-up period due to anxiety. However, active surveillance has indicated that a substantial proportion (range, 8-32%) of patients underwent surgery mainly due to anxiety. In a subset of PTMC patients who are high-risk surgical candidates or who refuse surgery, especially those who have failed or are reluctant to pursue active surveillance, thermal ablation can be a good option.
对于低危甲状腺微小乳头状癌（PTMC）患者，热消融治疗为除主动监测和即刻手术之外的一种治疗选择。在此，我们对热消融治疗 PTMC 的肿瘤学转归进行了综述，并与主动监测和手术进行了比较。
汇总 5 年随访数据显示，PTMC 患者行热消融治疗后未见肿瘤进展。热消融治疗的这种肿瘤学转归与即刻手术相当，但并发症更少。此外，随访期间没有因焦虑而接受延迟手术的行热消融治疗的患者。然而，主动监测表明，相当一部分（范围为 8%-32%）患者由于焦虑而接受了手术。对于高危手术候选者或拒绝手术的部分 PTMC 患者，特别是那些主动监测失败或不愿意进行主动监测的患者，热消融治疗可能是一种不错的选择。
