Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, 88 Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, Korea.
Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, 86 Asanbyeongwon-Gil, Songpa-gu, Seoul, 05505, Korea.
Curr Oncol Rep. 2022 Aug;24(8):1045-1052. doi: 10.1007/s11912-022-01268-2. Epub 2022 Apr 6.
PURPOSE OF REVIEW: Thermal ablation presents a therapeutic option other than active surveillance and immediate surgery for patients with low-risk papillary thyroid microcarcinomas (PTMC). Here, we have reviewed the current oncologic outcome of thermal ablation in PTMC cases and compared it with active surveillance and surgery. RECENT FINDINGS: Thermal ablation in PTMC cases revealed no tumor progression for pooled 5-year follow-up data. This oncologic outcome of thermal ablation was comparable to that of immediate surgery with less morbidity. Additionally, no patient who underwent thermal ablation received delayed surgery during the follow-up period due to anxiety. However, active surveillance has indicated that a substantial proportion (range, 8-32%) of patients underwent surgery mainly due to anxiety. In a subset of PTMC patients who are high-risk surgical candidates or who refuse surgery, especially those who have failed or are reluctant to pursue active surveillance, thermal ablation can be a good option.
目的综述:对于低危甲状腺微小乳头状癌(PTMC)患者,热消融治疗为除主动监测和即刻手术之外的一种治疗选择。在此,我们对热消融治疗 PTMC 的肿瘤学转归进行了综述,并与主动监测和手术进行了比较。
最新发现:汇总 5 年随访数据显示,PTMC 患者行热消融治疗后未见肿瘤进展。热消融治疗的这种肿瘤学转归与即刻手术相当,但并发症更少。此外,随访期间没有因焦虑而接受延迟手术的行热消融治疗的患者。然而,主动监测表明,相当一部分(范围为 8%-32%)患者由于焦虑而接受了手术。对于高危手术候选者或拒绝手术的部分 PTMC 患者,特别是那些主动监测失败或不愿意进行主动监测的患者,热消融治疗可能是一种不错的选择。
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