Scalvenzi Massimiliano, Villani Alessia, Mazzella Caterina, Fabbrocini Gabriella, Costa Claudia
Department of Dermatology, University of Naples Federico II, Naples, Italy.
Open Access Maced J Med Sci. 2019 Feb 20;7(4):696-697. doi: 10.3889/oamjms.2019.123. eCollection 2019 Feb 28.
Bowen's disease (BD), also known as squamous cell carcinoma in situ, is a type of non-melanocytic intraepidermal malignancy characterised by a slowly enlarging erythematous to pink, scaly patch or plaque with irregular and well-demarcated borders. These lesions are usually persistent and progressive; it has been estimated that in general population around 3% to 5% of Bowen's disease transform into invasive squamous cell carcinoma. This report describes our experience with cutaneous BD and assesses the differences found about age, sex and anatomical site. Bowen's disease was seen more frequently in male patients rather than in female patients in contrast to what confirmed in literature - this difference is probably because being head-neck an exposed region, patients are more easily induced to autoexam and to consult the dermatologist.
鲍温病（BD），也称为原位鳞状细胞癌，是一种非黑素细胞性表皮内恶性肿瘤，其特征为缓慢扩大的红斑至粉红色、鳞屑性斑片或斑块，边界不规则且清晰。这些病变通常持续存在并进展；据估计，在普通人群中，约3%至5%的鲍温病会转变为浸润性鳞状细胞癌。本报告描述了我们对皮肤鲍温病的经验，并评估了在年龄、性别和解剖部位方面发现的差异。与文献中证实的情况相反，鲍温病在男性患者中比在女性患者中更常见——这种差异可能是因为头颈部是暴露区域，患者更容易进行自我检查并咨询皮肤科医生。
