Nagakeerthana Sundar, Rajesh Gurumoorthy, Madhavi Sankar, Karthikeyan Kaliaperumal
Department of Dermatology, Sri Manakula Vinayagar Medical College and Hospital, Puducherry, India.
J Cancer Res Ther. 2017 Apr-Jun;13(2):371-373. doi: 10.4103/0973-1482.187237.
Bowen's disease is a form of intraepidermal squamous cell carcinoma (SCC). It usually presents as a well-demarcated, slow growing erythematous patch, or plaque with a scaly or crusted surface. The size of the tumor varies from a few millimeters to several centimeters. The risk of progression into an invasive carcinoma is 3-5% in extragenital lesions and about 10% in genital lesions. We present two cases of Bowen's disease where the pattern, size, and perception of the disease between the patients varied. The two cases demonstrated two varying spectrum of the disease, one being a giant lesion and other a dwarf. One patient was more concerned about the lesion, whereas the other patient neglected the lesions, though widespread. High index of suspicion is required to diagnose such atypical presentations of Bowen's disease. As Bowen's disease has tendency to progress to SCC, it should be diagnosed and treated as early as possible.
鲍温病是表皮内鳞状细胞癌(SCC)的一种形式。它通常表现为边界清晰、生长缓慢的红斑性斑片或斑块,表面有鳞屑或结痂。肿瘤大小从几毫米到几厘米不等。生殖器外病变进展为浸润性癌的风险为3% - 5%,生殖器病变约为10%。我们报告两例鲍温病病例,患者之间疾病的形态、大小和认知各不相同。这两例展示了该疾病的两种不同表现谱,一例为巨大病变,另一例为微小病变。一名患者更关注病变,而另一名患者尽管病变广泛却忽视了它们。诊断鲍温病的这种非典型表现需要高度的怀疑指数。由于鲍温病有发展为鳞状细胞癌的倾向,应尽早诊断和治疗。