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群体感应淬灭:牙菌斑生物膜中的信号干扰

Quorum quenching: Signal jamming in dental plaque biofilms.

作者信息

Basavaraju Mounika, Sisnity Vidya Sagar, Palaparthy Rajababu, Addanki Pavan Kumar

机构信息

Department of Periodontics, Kamineni Institute of Dental Sciences, Narketpally, Nalgonda, Telangana, 508254, India.

出版信息

J Dent Sci. 2016 Dec;11(4):349-352. doi: 10.1016/j.jds.2016.02.002. Epub 2016 Apr 11.

Abstract

Quorum sensing helps bacteria to communicate with each other and in coordinating their behavior. Many diseases of humans, plants, and animals are mediated by communication called quorum sensing. Various approaches are being investigated to inhibit this communication to control the diseases caused by bacteria. Periodontal pathogens also communicate through quorum sensing and new approaches to treat periodontal disease using quorum sensing inhibition need to be explored.

摘要

群体感应有助于细菌相互交流并协调它们的行为。许多人类、植物和动物疾病是由称为群体感应的交流介导的。正在研究各种方法来抑制这种交流,以控制由细菌引起的疾病。牙周病原体也通过群体感应进行交流,需要探索利用群体感应抑制来治疗牙周疾病的新方法。

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