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18F-FDG PET/CT 所见的儿童鼻咽癌

Pediatric Nasopharyngeal Carcinoma as Seen on 18F-FDG PET/CT.

作者信息

Muzaffar Razi, Vacca Francesca, Guo Huazhang, Mhapsekar Rishi, Osman Medhat M

机构信息

Division of Nuclear Medicine, Department of Radiology, Saint Louis University, Saint Louis, MO, United States.

Department of Pathology, Saint Louis University, Saint Louis, MO, United States.

出版信息

Front Oncol. 2019 Mar 6;9:110. doi: 10.3389/fonc.2019.00110. eCollection 2019.

Abstract

Pediatric nasopharyngeal carcinoma is a rare malignancy strongly associated with Epstein-Barr virus infection. Patients typically present with non-specific symptoms of epistaxis or serous otitis from eustachian tube obstruction and therefore diagnosis is often delayed. We present a case of a previously healthy 17 year old female who initially complained of migraines which was resistant to oral medication. Symptoms progressed and she saw a dental surgeon for concern of a dental infection and was prescribed antibiotics with no relief. Her symptoms continued to progress until an otolaryngologist visualized a large mass along the floor of the left nasal cavity. Subsequent imaging showed a large mass in the posterior left nasal cavity and biopsy was consistent with nasopharyngeal carcinoma.

摘要

儿童鼻咽癌是一种罕见的恶性肿瘤,与EB病毒感染密切相关。患者通常表现为鼻出血或咽鼓管阻塞引起的浆液性中耳炎等非特异性症状,因此诊断往往延迟。我们报告一例病例,一名17岁以前健康的女性,最初抱怨偏头痛,口服药物治疗无效。症状进展,她因担心牙齿感染去看了牙科医生,医生开了抗生素但没有缓解。她的症状持续进展,直到一名耳鼻喉科医生在左鼻腔底部发现一个大肿块。随后的影像学检查显示左鼻腔后部有一个大肿块,活检结果与鼻咽癌一致。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2d93/6414426/6c15b520072c/fonc-09-00110-g0001.jpg

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