Schudt F, Gross V, Sohrabi K, Fischer P, Hofmann S, Noeh C, Hildebrandt O, Koehler U
Fachbereich Gesundheit, Technische Hochschule Mittelhessen, Gießen.
Klinik für Innere Medizin, SP Pneumologie, Intensiv- und Schlafmedizin, Philipps-Universität, Marburg.
Pneumologie. 2019 Aug;73(8):465-469. doi: 10.1055/a-0859-4643. Epub 2019 Mar 20.
Respiratory rate is an important risk marker and enables early detection of critically ill and vulnerable patients in clinical routine. The aim of this pilot study with 31 patients (COPD severity levels II - IV) was to determine the mean nocturnal respiratory rate based on breath sound recordings and to investigate the dependence of respiratory rate on COPD severity level and smoker status. The mean respiratory rate of the total collective was 19/min. For the COPD-GOLD severity levels, no significant differences in mean respiratory rate could be observed. When nicotine consumption is taken into account, active smokers showed a significantly higher mean respiratory rate of 20.84 ± 4.45/min compared to non-smokers with 17.41 ± 3.14/min (p < 0.05). In addition, active smokers in the study were significantly more frequent among patients with night-time wheezing (60 % vs. 23.8 %). This might suggest that smokers need to perform increased breathing work with increased breathing rate to compensate for oxygen deficiency in bronchial obstruction. The results of the present study show that with the acoustic recording of breath sounds, a reliable representation and calculation of the breath frequency is possible.
呼吸频率是一项重要的风险指标，有助于在临床常规中早期发现重症和易患患者。这项针对31名患者（慢性阻塞性肺疾病（COPD）严重程度为II-IV级）的试点研究旨在根据呼吸音记录确定夜间平均呼吸频率，并研究呼吸频率与COPD严重程度和吸烟状况的相关性。整个研究群体的平均呼吸频率为19次/分钟。对于COPD-GOLD严重程度分级，未观察到平均呼吸频率有显著差异。考虑到尼古丁摄入量，与非吸烟者（平均呼吸频率为17.41±3.14次/分钟）相比，主动吸烟者的平均呼吸频率显著更高，为20.84±4.45次/分钟（p<0.05）。此外，在夜间喘息患者中，主动吸烟者更为常见（60%对23.8%）。这可能表明吸烟者需要通过增加呼吸频率来增加呼吸功，以补偿支气管阻塞导致的缺氧。本研究结果表明，通过呼吸音的声学记录，可以可靠地呈现和计算呼吸频率。
