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针灸治疗韩国乳腺癌幸存者症状管理:一项前瞻性试点研究。

Acupuncture for symptoms management in Korean breast cancer survivors: a prospective pilot study.

机构信息

1 Korean Medicine Clinical Trial Center, Korean Medicine Hospital, Kyung Hee University, Seoul, South Korea.

2 Department of Acupuncture & Moxibustion, College of Korean Medicine, Kyung Hee University, Seoul, South Korea.

出版信息

Acupunct Med. 2019 Jun;37(3):164-174. doi: 10.1177/0964528419832610. Epub 2019 Mar 21.

Abstract

BACKGROUND

There is an unmet need for effective treatment of the various treatment-related symptoms experienced by breast cancer survivors. These symptoms could be alleviated by acupuncture. Although several lines of evidence in Western countries suggest that acupuncture has a beneficial effect on symptoms in breast cancer survivors, few relevant studies have been conducted in Korean patients. This pilot study assessed the feasibility of acupuncture for a variety of treatment-related symptoms in Korean breast cancer survivors.

METHOD

From October 2015 to March 2016, we recruited patients who had undergone treatment for breast cancer and subsequently reported symptoms, including aromatase inhibitor-related knee pain, vasomotor symptoms, insomnia, sexual dysfunction and post-mastectomy pain in the chest wall or shoulder. The women received 4 weeks of symptom-specific acupuncture followed by a further 4 weeks of follow-up to evaluate the feasibility of acupuncture for this indication, and its impact on common and symptom-specific outcome variables.

RESULTS

Eight study participants were recruited over a period of 6 months, six of whom completed the planned acupuncture treatment and follow-up assessments. A total of 78 acupuncture sessions were performed. We found that acupuncture was feasible, with only six minor self-limiting acupuncture-related adverse events. Most of the women felt that they had benefitted from participation in the study. The preliminary analysis indicated improvement in common symptom-specific outcomes.

CONCLUSION

Our findings suggest that acupuncture is feasible, but low recruitment rates should be considered when considering future acupuncture research in Korean breast cancer survivors. Rigorous evaluation of this symptomatic treatment strategy is now needed in the Korean population.

摘要

背景

乳腺癌幸存者在治疗过程中会出现各种治疗相关症状,这些症状需要有效的治疗手段来缓解。针灸可能对此有效。尽管西方国家有大量证据表明针灸对乳腺癌幸存者的症状有有益影响,但在韩国患者中进行的相关研究较少。本研究评估了针灸治疗韩国乳腺癌幸存者各种治疗相关症状的可行性。

方法

2015 年 10 月至 2016 年 3 月,我们招募了接受过乳腺癌治疗并报告有症状的患者,包括芳香化酶抑制剂相关的膝痛、血管舒缩症状、失眠、性功能障碍以及乳房切除术或肩部胸壁术后疼痛。这些患者接受了 4 周的对症针灸治疗,然后进行了另外 4 周的随访,以评估针灸治疗这种病症的可行性,及其对常见和症状特异性结局变量的影响。

结果

在 6 个月的时间里,共招募了 8 名研究参与者,其中 6 名完成了计划的针灸治疗和随访评估。共进行了 78 次针灸治疗。我们发现针灸是可行的,只有 6 例轻微的与针灸相关的自限性不良事件。大多数女性认为她们从参与研究中受益。初步分析表明,常见的症状特异性结局有所改善。

结论

我们的研究结果表明针灸是可行的,但在考虑未来韩国乳腺癌幸存者的针灸研究时,应考虑到低招募率。现在需要在韩国人群中对这种对症治疗策略进行严格的评估。

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