1Vanderbilt University School of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.
2Medical Scientist Training Program, Vanderbilt University Medical Center, Nashville, Tennessee.
Tissue Eng Part B Rev. 2019 Aug;25(4):259-290. doi: 10.1089/ten.TEB.2018.0325.
The use of autologous tissue in the reconstruction of tissue defects has been the gold standard. However, current standards still face many limitations and complications. Improving patient outcomes and quality of life by addressing these barriers remain imperative. This article provides historical perspective, covers the major limitations of current standards of care, and reviews recent advances and future prospects in applied bioengineering in the context of tissue reconstruction, replacement, and regeneration.
自体组织在组织缺损重建中的应用一直是金标准。然而，目前的标准仍然面临许多限制和并发症。通过解决这些障碍来改善患者的预后和生活质量仍然至关重要。本文提供了历史背景，涵盖了当前护理标准的主要局限性，并回顾了组织重建、替代和再生领域应用生物工程的最新进展和未来前景。
