Sapbamrer Ratana, Thongtip Sakesun, Khacha-Ananda Supakit, Sittitoon Nalin, Wunnapuk Klintean
Department of Community Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
School of Medicine, University of Phayao, Phayao, Thailand.
Arch Environ Occup Health. 2020;75(2):88-97. doi: 10.1080/19338244.2019.1577208. Epub 2019 Mar 21.
Exposure to pesticides via inhalation might impair lung function and develop further severe respiratory symptoms and diseases. Thus, the purpose of the study was to compare lung function between pre- and post-pesticide spraying seasons among male sprayers. The study also evaluated the association of lung function changes and other factors with respiratory symptoms. The follow-up study was conducted on 58 male sprayers. The subjects were interviewed and measured lung function before and after pesticide spraying season. The results found that forced vital capacity (FVC), forced expiratory volume in one second (FEV), and peak expiratory flow rate in the post-spraying season were significantly lower than in the pre-spraying season. With regard to respiratory symptoms, cough symptoms were associated with changes in FEV/FVC [odd ratio (OR) = 1.29, 95% confidence interval (CI) = 1.01-1.67)] and smoking status (OR = 12.95, 95%CI = 1.35-124.34). Phlegm symptoms were also associated with changes in FVC (OR = 2.07, 95%CI = 1.01-4.25) and FEV (OR = 0.41, 95%CI = 0.18-0.91). The study provides evidence that pesticide spraying may increase risks for significant alteration of lung function and respiratory symptoms.
通过吸入接触农药可能会损害肺功能，并引发更严重的呼吸道症状和疾病。因此，本研究的目的是比较男性喷雾器操作人员在农药喷洒季节前后的肺功能。该研究还评估了肺功能变化及其他因素与呼吸道症状之间的关联。对58名男性喷雾器操作人员进行了随访研究。在农药喷洒季节前后对受试者进行了访谈并测量了肺功能。结果发现，喷洒后季节的用力肺活量（FVC）、一秒用力呼气容积（FEV）和呼气峰值流速显著低于喷洒前季节。关于呼吸道症状，咳嗽症状与FEV/FVC的变化[比值比（OR）=1.29，95%置信区间（CI）=1.01 - 1.67]和吸烟状况（OR = 12.95，95%CI = 1.35 - 124.34）相关。咳痰症状也与FVC的变化（OR = 2.07，95%CI = 1.01 - 4.25）和FEV的变化（OR = 0.41，95%CI = 0.18 - 0.91）相关。该研究提供了证据表明，农药喷洒可能会增加肺功能显著改变和呼吸道症状的风险。
