Lee Sooyeon, Han Jiyoung, Woo Seung Hee, Lee Soo-Jin
Department of Occupational and Environmental Medicine, Hanyang University Hospital, Seoul, Korea.
Department of Occupational and Environmental Medicine, Hanyang University College of Medicine, Seoul, Korea.
Ann Occup Environ Med. 2022 Dec 8;34:e42. doi: 10.35371/aoem.2022.34.e42. eCollection 2022.
Occupational pesticide exposure is a potential risk for respiratory health effects. Most clinical studies on pesticide exposure were related to acute exposure, and only a few studies on chronic exposure have been conducted. This study investigated the chronic respiratory health status and the chronic effects of occupational pesticide exposures of farmers in Gyeonggi-do.
Surveys and pulmonary function tests were conducted on 1,697 farmers in 16 regions of Gyeonggi-do. The structured questionnaire included demographic characteristics, medical history, recent respiratory symptoms and diseases, and work-related conditions, and was conducted through one-on-one interviews. The prevalence of respiratory diseases was compared by the odds ratios (ORs) at 95% confidence intervals (CIs) estimated by logistic regression analysis. Additional multivariate logistic regression analysis was also conducted.
Pesticide work groups showed significant association with an obstructive pattern in the lung function test (unadjusted OR, 2.38; 95% CI, 1.17-5.52). Selected work-related variables of pesticide exposure were 'start age,' 'cumulative duration,' 'mixing pesticides,' and 'protection(goggle).' The obstructive pattern of lung function test showed significant associations with mixing pesticides (OR, 2.30; 95% CI,1.07-5.46), and protection (goggle) use (OR, 0.34; 95% CI, 0.12-0.79).
Mixing two or more pesticides showed a significant association. Wearing goggles can be seen as an indicator of awareness of the protective equipment and proper wearing of protective equipment, and loss of pulmonary function can be prevented when appropriate protection is worn.
职业性接触农药是呼吸系统健康影响的潜在风险。大多数关于农药接触的临床研究都与急性接触有关，而关于慢性接触的研究较少。本研究调查了京畿道农民的慢性呼吸系统健康状况以及职业性农药接触的慢性影响。
对京畿道16个地区的1697名农民进行了调查和肺功能测试。结构化问卷包括人口统计学特征、病史、近期呼吸道症状和疾病以及与工作相关的情况，并通过一对一访谈进行。通过逻辑回归分析估计的95%置信区间（CI）的比值比（OR）比较呼吸道疾病的患病率。还进行了额外的多变量逻辑回归分析。
农药作业组在肺功能测试中与阻塞性模式有显著关联（未调整的OR，2.38；95%CI，1.17 - 5.52）。选定的与农药接触相关的工作变量为“开始年龄”、“累积持续时间”、“混合农药”和“防护（护目镜）”。肺功能测试的阻塞性模式与混合农药（OR，2.30；95%CI，1.07 - 5.46）和使用防护（护目镜）（OR，0.34；95%CI，0.12 - 0.79）有显著关联。
混合两种或更多种农药显示出显著关联。佩戴护目镜可被视为对防护设备的认知和正确佩戴防护设备的指标，适当佩戴防护设备可预防肺功能丧失。
