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番木瓜叶提取物在新生儿血小板减少症中的应用。

Use of papaya leaf extract in neonatal thrombocytopenia.

作者信息

Pandita Aakash, Mishra Namita, Gupta Girish, Singh Rachna

机构信息

Department of Neonatology Sanjay Gandhi Post Graduate Institute of Medical Sciences Lucknow India.

出版信息

Clin Case Rep. 2019 Feb 1;7(3):497-499. doi: 10.1002/ccr3.2025. eCollection 2019 Mar.

DOI:10.1002/ccr3.2025
PMID:30899480
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6406160/
Abstract

Thrombocytopenia is a common condition in neonates. Neonatal thrombocytopenia can cause serious complications such as intraventricular hemorrhage. Papaya leaf extract may be a safe and effective therapy in persistent refractory neonatal thrombocytopenia. Papaya leaf extract was effective for improving platelet count in our baby with persistent thrombocytopenia. However, with no previous evidence of its use in neonates, its use is still experimental and should only be considered in refractory cases after team meeting and detailed discussion with family.

摘要

血小板减少症在新生儿中是一种常见病症。新生儿血小板减少症可引发严重并发症,如脑室内出血。番木瓜叶提取物可能是治疗持续性难治性新生儿血小板减少症的一种安全有效的疗法。番木瓜叶提取物对提高我们患有持续性血小板减少症的婴儿的血小板计数有效。然而,由于此前没有其用于新生儿的证据,其使用仍处于试验阶段,仅应在团队会诊并与家属进行详细讨论后,在难治性病例中予以考虑。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f90d/6406160/405e490e077b/CCR3-7-497-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f90d/6406160/d003da19a7c1/CCR3-7-497-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f90d/6406160/405e490e077b/CCR3-7-497-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f90d/6406160/d003da19a7c1/CCR3-7-497-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f90d/6406160/405e490e077b/CCR3-7-497-g002.jpg

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Integr Med (Encinitas). 2019 Oct;18(5):30-35.
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Int J Appl Basic Med Res. 2016 Oct-Dec;6(4):249-254. doi: 10.4103/2229-516X.192596.
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A Multi-centric, Double-blind, Placebo-controlled, Randomized, Prospective Study to Evaluate the Efficacy and Safety of Carica papaya Leaf Extract, as Empirical Therapy for Thrombocytopenia associated with Dengue Fever.
Molecules. 2022 Apr 25;27(9):2760. doi: 10.3390/molecules27092760.
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A Case Study Using Papaya Leaf Extract to Reverse Chemotherapy-Induced Thrombocytopenia in a GBM Patient.木瓜叶提取物逆转 GBM 患者化疗诱导血小板减少症的病例研究。
Integr Cancer Ther. 2022 Jan-Dec;21:15347354211068417. doi: 10.1177/15347354211068417.
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L. Leaf: A Systematic Scoping Review on Biological Safety and Herb-Drug Interactions.L. 利夫:关于生物安全性和草药 - 药物相互作用的系统综述。
Evid Based Complement Alternat Med. 2021 May 7;2021:5511221. doi: 10.1155/2021/5511221. eCollection 2021.
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Dengue Fever: Therapeutic Potential of L. Leaves.登革热:L. 叶的治疗潜力
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