Lemmens Roel, Devreker Thierry, Hauser Bruno, Degreef Elisabeth, Goossens Annieta, Vandenplas Yvan
Kidz Health Castle, UZ Brussel, Vrije Universiteit Brussel, Brussels, Belgium.
Department of Pathology, UZ Brussel, Vrije Universiteit Brussel, Brussels, Belgium.
Pediatr Gastroenterol Hepatol Nutr. 2019 Mar;22(2):193-200. doi: 10.5223/pghn.2019.22.2.193. Epub 2019 Mar 8.
A clinical suspicion of intestinal spirochetosis is required when patients have long lasting complaints of abdominal pain, diarrhea, rectal bleeding, weight loss, and nausea. An endoscopy with biopsies needs to be performed to confirm the diagnosis of intestinal spirochetosis. The diagnosis of intestinal spirochetosis is based on histological appearance. Intestinal spirochetosis can also be associated with other intestinal infections and juvenile polyps (JPs). JPs seem to be more frequent in patients with intestinal spirochetosis than in patients without intestinal spirochetosis. Intestinal spirochetosis in children should be treated with antibiotics. Metronidazole is the preferred option. In this article, we describe 4 cases of intestinal spirochetosis in a pediatric population and provide a review of the literature over the last 20 years. Intestinal spirochetosis is a rare infection that can cause a variety of severe symptom. It is diagnosed based on histological appearance.
当患者长期主诉腹痛、腹泻、直肠出血、体重减轻和恶心时,需要临床怀疑肠道螺旋体病。需要进行内镜检查及活检以确诊肠道螺旋体病。肠道螺旋体病的诊断基于组织学表现。肠道螺旋体病还可能与其他肠道感染和幼年息肉(JPs)有关。幼年息肉在肠道螺旋体病患者中似乎比在无肠道螺旋体病的患者中更常见。儿童肠道螺旋体病应使用抗生素治疗。甲硝唑是首选药物。在本文中,我们描述了4例儿科患者的肠道螺旋体病病例,并对过去20年的文献进行了综述。肠道螺旋体病是一种罕见的感染,可导致多种严重症状。它是根据组织学表现来诊断的。