Ho Kimberly, Xu Joseph, Katz Seymour, Sarkar Suparna A, Mujeeb Ullah Ateeqa
Department of Pathology, New York University (NYU) Langone Health, Mineola, USA.
Department of Internal Medicine, University of California Davis, Sacramento, USA.
Cureus. 2024 Jan 30;16(1):e53248. doi: 10.7759/cureus.53248. eCollection 2024 Jan.
Spirochete colonization of the gastrointestinal tract is a poorly understood phenomenon presenting with varying signs and symptoms. Due to the lack of a unified approach and its varying presentations, the management decision for intestinal spirochetosis (IS) has always been challenging. While metronidazole is the commonly preferred antimicrobial treatment, it remains unclear if therapeutic intervention is indicated for everyone, especially asymptomatic patients. We present three patients, diagnosed with IS. They presented with varying demographics, clinical presentations, and past medical histories and underwent different clinical managements. Our decisions for treatment not only included presenting symptoms but also factors like history of pre-existing gastrointestinal diseases, age, and immune status.
胃肠道螺旋体定植是一种了解甚少的现象，其症状和体征各异。由于缺乏统一的方法以及表现形式多样，肠道螺旋体病（IS）的治疗决策一直具有挑战性。虽然甲硝唑是常用的首选抗菌治疗药物，但对于每个人，尤其是无症状患者是否需要进行治疗干预仍不明确。我们报告了三名被诊断为IS的患者。他们的人口统计学特征、临床表现和既往病史各不相同，并接受了不同的临床管理。我们的治疗决策不仅包括呈现出的症状，还包括诸如既往胃肠道疾病史、年龄和免疫状态等因素。
