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七鳃鳗抽动肌纤维中动作电位通过T管系统的传播。

The spread of the action potential through the T-system in hagfish twitch muscle fibres.

作者信息

Nicolaysen K

出版信息

Acta Physiol Scand. 1976 Jan;96(1):29-49. doi: 10.1111/j.1748-1716.1976.tb10168.x.

DOI:10.1111/j.1748-1716.1976.tb10168.x
PMID:3090
Abstract

The input impedance of twitch muscle fibres of the Atlantic hagfish has been measured with sinusoidal transmembrane currents. The apparent specific membrane resistance and capacitance decreased markedly with frequency, and were relatively independent of fibre diameter. A model of the T-system based on anatomical observations, was used to predict the input impedance in the normal solution (artificial sea water). The changes in input impedance produced by glycerol treatment, low chloride solution, reduced pH and isotonic solutions with low ionic strength were easily interpreted in terms of the same model. The model predicts severe attenuation of the action potential if conducted electrotonically by the transverse tubules towards the center of the fibre.

摘要

已通过正弦跨膜电流测量了大西洋盲鳗抽搐肌纤维的输入阻抗。表观比膜电阻和电容随频率显著降低,且相对与纤维直径无关。基于解剖学观察建立的T管系统模型,用于预测正常溶液(人工海水)中的输入阻抗。甘油处理、低氯溶液、pH值降低以及低离子强度的等渗溶液所产生的输入阻抗变化,根据同一模型很容易得到解释。该模型预测,如果动作电位通过横管以电紧张方式向纤维中心传导,将会严重衰减。

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引用本文的文献

1
Distribution and dimension of the T-system in different muscle fiber types in the atlantic hagfish (Myxine glutinosa, L.).大西洋盲鳗(Myxine glutinosa, L.)不同肌纤维类型中T系统的分布与尺寸
Cell Tissue Res. 1975;157(1):1-16. doi: 10.1007/BF00223227.