Kim Jin-Woo, Kim Dong-Hyun, Jang Eui-Chan, Lee Young-Kyun, Koo Kyung-Hoi, Ha Yong-Chan
Department of Orthopaedic Surgery, Eulji Medical Center, Eulji University College of Medicine, Seoul, South Korea.
Department of Orthopaedic Surgery, Chung-Ang University College of Medicine, Seoul, South Korea.
J Orthop Sci. 2019 Sep;24(5):850-854. doi: 10.1016/j.jos.2019.02.019. Epub 2019 Mar 20.
The purpose of this study was to assess mortality with a minimum of 2-year follow-up, related risk factors for mortality, and functional outcomes after surgical interventions in nonagenarian patients with hip fractures at the latest follow up.
Between June 2003 and November 2015, 260 nonagenarians (271 hips) with femoral neck and intertrochanteric fractures were included in this retrospective study. Cumulative mortality using the Kaplan-Meier method and risk factors for mortality using Cox proportional-hazards regression model were estimated. As functional outcome, ambulatory ability was assessed before injury and at the latest follow-up.
Six-teen patients (16 hips) were lost to follow-up. The mean age at the time of surgery was 92.2 years (range 90-108 years). Mortality rates were 23.4% (57 of 244 patients) at 1 year and 40.6% (99 of 244 patients) at 2 years. Both genders had elevated standardized mortality ratio at 2-year post-fracture compared to that a 1-year post fracture. Multivariate analysis showed that American Society of Anesthesiologists (OR, 1.371; 95% CI, 1.021-1.843; P = 0.036) and time interval from trauma to operation (OR, 1.043; 95% CI, 1.002-1.086; P = 0.039) were significantly associated with risk of mortality. Of 58 patients alive, 13 patients (22.4%) had the same ambulatory ability before and after injury.
This study demonstrates that mortality is higher in nonagenarians with hip fracture. Risk factors for mortality in nonagenarians with hip fracture are American Society of Anesthesiologists and time interval from trauma to operation. And, nonagenarians with hip fractures have lower rate of maintaining pre-injury ambulatory ability.
本研究旨在评估至少随访2年的死亡率、死亡相关危险因素以及在最新随访时非agenarian老年髋部骨折患者手术干预后的功能结局。
在2003年6月至2015年11月期间,260例患有股骨颈和转子间骨折的非agenarian老年人(271髋)被纳入这项回顾性研究。使用Kaplan-Meier方法估计累积死亡率,并使用Cox比例风险回归模型估计死亡危险因素。作为功能结局,在受伤前和最新随访时评估行走能力。
16例患者(16髋)失访。手术时的平均年龄为92.2岁(范围90 - 108岁)。1年时死亡率为23.4%(244例患者中的57例),2年时为40.6%(244例患者中的99例)。与骨折后1年相比,骨折后2年时男女的标准化死亡率均升高。多变量分析显示,美国麻醉医师协会分级(OR,1.371;95%CI,1.021 - 1.843;P = 0.036)和从创伤到手术的时间间隔(OR,1.043;95%CI,1.002 - 1.086;P = 0.039)与死亡风险显著相关。在58例存活患者中,13例患者(22.4%)受伤前后的行走能力相同。
本研究表明,老年髋部骨折患者的死亡率较高。老年髋部骨折患者的死亡危险因素是美国麻醉医师协会分级和从创伤到手术的时间间隔。而且,老年髋部骨折患者维持受伤前行走能力的比例较低。