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超高龄与高龄患者髋关节骨折手术后的结局:1524 例患者匹配队列分析。

Outcomes of ultra-old vs old patients after hip fracture surgery: a matched cohort analysis of 1524 patients.

机构信息

Department of Orthopedic Surgery, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, Singapore, 308433, Singapore.

出版信息

Arch Orthop Trauma Surg. 2023 Jun;143(6):3145-3154. doi: 10.1007/s00402-022-04550-x. Epub 2022 Jul 21.

DOI:10.1007/s00402-022-04550-x
PMID:35864337
Abstract

BACKGROUND

Surgical management of geriatric hip fractures yields improved functional outcomes with decreased morbidity and mortality. Cohort studies have suggested that the older patients within the geriatric age group have worse outcomes with surgery, However, these studies inherently report inflated risks due to poor handling of confounders and have inadequately age-stratified their geriatric population.

AIM

This study aims to investigate the effect of age alone on the 1-year mortality and functional status of geriatric patients after hip fracture surgery.

METHODS

This is a retrospective single institution cohort study based on the prospectively-maintained registry of hip fracture patients. 2603 patients aged 60 years and above were treated surgically under a geriatric-orthopaedic hip fracture pathway from January 2014 to December 2018. Patients were split into two age groups: ultra-old (≥ 85 years) vs old (< 85 years). Baseline demographics and the ASA (American Society of Anaesthesiologists) status and the Modified Barthel's Index (MBI) were obtained at admission and 1 year after the fracture. Adverse outcomes from the fracture and surgery were recorded during a follow-up period of minimally 2 years. A 2:1 matching process based on the gender, fracture type, ASA status, CCI and MBI categories was conducted.

RESULTS

There were 1009 and 515 patients in the old and ultra-old age groups, respectively. 1-year mortality was similar for both age groups (4.0% ultra-old vs 3.6% old, p = 0.703). 30-day morbidity was similar except for higher rates of postoperative pneumonia in the ultra-old (14.0 vs 6.3%, p < 0.001). MBI scores at 1-year were lower in the ultra-old (severe dependence: 16.4 vs 10.0%; p = 0.001). Ultra-old patients were less likely to be community ambulant at 12 months (21.2 vs 36.0%) with the deterioration in ambulatory status significant after correction for baseline status (p < 0.001).

CONCLUSION

The 1-year mortality of surgically-managed geriatric hip fracture patients older than 85 years of age is not determined by age alone. Patients aged 85 years and above are at higher risk for pneumonia postoperatively. Ultra-old hip fracture patients with an intertrochanteric fracture are more likely to have poorer function at 1 year after hip fracture surgery.

摘要

背景

老年髋部骨折的手术治疗可改善功能结局,降低发病率和死亡率。队列研究表明,老年人群中年龄较大的患者手术治疗效果较差,但这些研究由于对混杂因素处理不当,以及对老年人群未进行充分的年龄分层,因此报告的风险过高。

目的

本研究旨在探讨年龄因素对老年髋部骨折手术后患者 1 年死亡率和功能状态的影响。

方法

这是一项基于前瞻性维护的髋部骨折患者登记处的回顾性单中心队列研究。2014 年 1 月至 2018 年 12 月,2603 名年龄在 60 岁及以上的患者通过老年骨科髋部骨折途径接受手术治疗。患者分为两组:超高龄组(≥85 岁)和高龄组(<85 岁)。在骨折和手术后的随访期至少为 2 年的情况下,记录骨折和手术的不良预后。根据性别、骨折类型、ASA 状态、CCI 和 MBI 类别,进行了 2:1 的匹配过程。

结果

高龄组和超高龄组分别有 1009 例和 515 例患者。两组 1 年死亡率相似(超高龄组 4.0%,高龄组 3.6%,p=0.703)。除超高龄组术后肺炎发生率较高(14.0%比 6.3%,p<0.001)外,30 天发病率相似。超高龄组患者在 1 年时的 MBI 评分较低(严重依赖:16.4%比 10.0%;p=0.001)。12 个月时,超高龄组患者社区活动能力较差的比例较低(21.2%比 36.0%),但在纠正基线状态后,活动状态恶化有统计学意义(p<0.001)。

结论

85 岁以上接受手术治疗的老年髋部骨折患者的 1 年死亡率并非仅由年龄决定。85 岁及以上患者术后发生肺炎的风险较高。股骨转子间骨折超高龄髋部骨折患者术后 1 年功能更差。

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J Orthop Surg Res. 2021 Oct 30;16(1):653. doi: 10.1186/s13018-021-02807-6.
2
Age and clinical outcomes after hip fracture surgery: do octogenarian, nonagenarian and centenarian classifications matter?髋部骨折手术后的年龄和临床结局:是否需要使用 80 岁以上、90 岁以上和 100 岁以上的分类?
Age Ageing. 2021 Nov 10;50(6):1952-1960. doi: 10.1093/ageing/afab137.
3
Functional Outcomes of Patients with Schizophrenia After Hip Fracture Surgery: A 1-Year Follow-up from an Institutional Hip Fracture Registry.
老年髋部骨折患者尿路感染的危险因素:一项系统评价和荟萃分析。
Front Med (Lausanne). 2024 Feb 9;11:1360058. doi: 10.3389/fmed.2024.1360058. eCollection 2024.
4
Efficacy of surgical intervention over conservative management in intertrochanteric fractures among nonagenarians and centenarians: a prospective cohort study.手术干预与保守治疗在 90 岁及以上高龄股骨转子间骨折患者中的疗效比较:一项前瞻性队列研究。
Int J Surg. 2024 May 1;110(5):2708-2720. doi: 10.1097/JS9.0000000000001143.
5
In-hospital outcomes following primary and revision total hip arthroplasty in nonagenarian patients.九十岁以上患者初次和翻修全髋关节置换术后的院内转归。
Arch Orthop Trauma Surg. 2024 Jan;144(1):475-481. doi: 10.1007/s00402-023-05032-4. Epub 2023 Aug 27.
精神分裂症患者髋关节骨折手术后的功能结局:来自机构髋关节骨折登记处的 1 年随访。
J Bone Joint Surg Am. 2021 May 5;103(9):786-794. doi: 10.2106/JBJS.20.01652.
4
Nonagenarian hip fractures: Morbidity and mortality at a single institution.九旬老人髋部骨折:单机构的发病率和死亡率
J Clin Orthop Trauma. 2020 Sep 22;14:69-73. doi: 10.1016/j.jcot.2020.09.020. eCollection 2021 Mar.
5
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PLoS Med. 2020 Aug 6;17(8):e1003180. doi: 10.1371/journal.pmed.1003180. eCollection 2020 Aug.
9
Operative Fixation of Hip Fractures in Nonagenarians: Is It Safe?非高龄患者髋部骨折的手术固定:安全吗?
J Arthroplasty. 2020 Nov;35(11):3180-3187. doi: 10.1016/j.arth.2020.06.005. Epub 2020 Jun 9.
10
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