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Increase of "antianxiety" activity and tolerance of behavioral depression during chronic administration of oxazepam.

作者信息

Margules D L, Stein L

出版信息

Psychopharmacologia. 1968;13(1):74-80. doi: 10.1007/BF00401620.

DOI:10.1007/BF00401620
PMID:5675460
Abstract
摘要

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Increase of "antianxiety" activity and tolerance of behavioral depression during chronic administration of oxazepam.在长期服用奥沙西泮期间“抗焦虑”活性增加及行为性抑郁耐受性增强。
Psychopharmacologia. 1968;13(1):74-80. doi: 10.1007/BF00401620.
2
Development of tolerance to benzodiazepines. II. Baclofen effect on the activity of rats during tolerance to the sedative action of nitrazepam and oxazepam.苯二氮䓬类耐受性的发展。II. 巴氯芬对大鼠在对硝西泮和奥沙西泮镇静作用产生耐受性期间活动的影响。
Acta Physiol Pol. 1984 Jul-Aug;35(4):301-9.
3
An anxiolytic-like effect of ondansetron disappears in oxazepam-tolerant rats.昂丹司琼的抗焦虑样作用在对奥沙西泮耐受的大鼠中消失。
Pharmacol Biochem Behav. 1998 Apr;59(4):935-8. doi: 10.1016/s0091-3057(97)00520-0.
4
Influence of N1-2-hydroxyethyl substitution on central activity of oxazepam and lorazepam.N1-2-羟乙基取代对奥沙西泮和劳拉西泮中枢活性的影响。
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5
Subacute benzodiazepine treatment: observations on behavioural tolerance and withdrawal.亚急性苯二氮䓬治疗：关于行为耐受性和戒断的观察
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6
[Comparison of the effects of di-n-propylacetate and oxazepam on spontaneous and conditioned responses in mice].[二正丙基乙酸酯与奥沙西泮对小鼠自发反应和条件反应影响的比较]
C R Acad Hebd Seances Acad Sci D. 1975 Oct 20;281(16):1175-8.
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Schedule-dependent differences among anti-anxiety drugs.
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Precipitated withdrawal in squirrel monkeys after repeated daily oral administration of alprazolam, diazepam, flunitrazepam or oxazepam.松鼠猴每日重复口服阿普唑仑、地西泮、氟硝西泮或奥沙西泮后出现戒断反应。
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Conflict behavior in a heated-floor maze: effects of oxazepam.热板迷宫中的冲突行为：奥沙西泮的作用
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Disruption of a temporal discrimination by the minor tranquilizer, oxazepam.弱安定药奥沙西泮对时间辨别力的干扰。
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本文引用的文献

1
A comparative study of certain pharmacologic responses following acute and chronic administrations of chlordiazepoxide.氯氮䓬急性与慢性给药后某些药理反应的比较研究。
Life Sci. 1967 Mar 1;6(5):481-91. doi: 10.1016/0024-3205(67)90051-3.
2
Metabolism and tolerance studies with chlordiazepoxide-2-l4C in the rat.大鼠体内氯氮䓬 -2-¹⁴C的代谢及耐受性研究。
Toxicol Appl Pharmacol. 1966 Jul;9(1):116-23. doi: 10.1016/0041-008x(66)90036-6.
3
Management of the office patient with anxiety and depression.焦虑和抑郁门诊患者的管理
使用松鼠猴的惩罚性反应和咪达唑仑辨别程序对大麻素激动剂进行评估。
Psychopharmacology (Berl). 2008 Jul;198(4):521-8. doi: 10.1007/s00213-007-0918-5. Epub 2007 Sep 19.
4
Development of tolerance to anxiolytic effects of chlordiazepoxide in elevated plus-maze test and decrease of GABAA receptors.在高架十字迷宫试验中对氯氮卓抗焦虑作用产生耐受性以及γ-氨基丁酸A型（GABAA）受体减少
J Neural Transm Gen Sect. 1993;91(1):27-37. doi: 10.1007/BF01244916.
5
Neuropharmacology of a new potential anxiolytic compound, F 2692, 1-(3'-trifluoromethyl phenyl) 1, 4-dihydro 3-amino 4-oxo 6-methyl pyridazine. 2. Evaluation of its tolerance and dependence producing potential and of its effects on benzodiazepine withdrawal in the elevated plus-maze test in rats.新型潜在抗焦虑化合物F 2692（1-(3'-三氟甲基苯基)-1,4-二氢-3-氨基-4-氧代-6-甲基哒嗪）的神经药理学。2. 在大鼠高架十字迷宫试验中对其产生耐受性和依赖性的潜力以及对苯二氮䓬戒断影响的评估。
Psychopharmacology (Berl). 1993;110(1-2):19-26. doi: 10.1007/BF02246946.
6
Tolerance, cross-tolerance and dependence measured by operant responding in rats treated with triazolam via osmotic pumps.通过渗透泵给大鼠注射三唑仑后，用操作性反应测量耐受性、交叉耐受性和依赖性。
Psychopharmacology (Berl). 1994 Jun;115(1-2):86-94. doi: 10.1007/BF02244756.
7
Differential regulation of the behavioral effects of chlordiazepoxide.氯氮䓬行为效应的差异调节。
Psychopharmacology (Berl). 1994 Jun;115(1-2):37-45. doi: 10.1007/BF02244749.
8
Hyponeophagia and arousal in rats: effects of diazepam, 5-methoxy-N,N-dimethyltryptamine, d-amphetamine and food deprivation.
Psychopharmacology (Berl). 1982;78(4):368-72. doi: 10.1007/BF00433744.
9
Changes in ambulatory activities and muscle relaxation in rats after repeated doses of diazepam.重复给予地西泮后大鼠的动态活动和肌肉松弛的变化。
Psychopharmacology (Berl). 1982;77(3):279-83. doi: 10.1007/BF00464580.
10
Effects of pentobarbital on punished behavior: persistent increases with chronic administration.
Psychopharmacology (Berl). 1981;75(3):324-5. doi: 10.1007/BF00432448.
Psychosomatics. 1965 Sep-Oct;6(5):347-51. doi: 10.1016/s0033-3182(65)72254-8.