Pesce C M
Public Health Rep. 1986 Jul-Aug;101(4):417-9.
Histopathology may serve a wide spectrum of diagnostic purposes in tropical medicine other than for infectious and parasitic diseases. In addition, it is essential in defining new pathological entities and collecting statistical data on morbidity and mortality. It should also constitute a basic support for advancement and research in tropical diseases. For practical purposes, both histopathology and cytopathology are often more effective than clinical chemistry and microbiology in providing the clinician with a final diagnosis. They do not rely on complicated and delicate equipment, and the few reagents they require can be stored indefinitely. Formalin fixation permits most histological methods to be used, including special stains and immunohistochemistry. Formalin-fixed material can be examined several days after excision. Implementing pathology laboratories in tropical countries may constitute a practical, cost-effective approach to the planning of diagnostic services at the regional or district level. A fraction of the medical graduates in developing countries should be devoted to the staffing of these laboratories.
组织病理学在热带医学中可用于广泛的诊断目的,而非仅用于感染性和寄生虫疾病。此外,它对于定义新的病理实体以及收集发病率和死亡率的统计数据至关重要。它还应为热带疾病的进展和研究提供基础支持。出于实际目的,在为临床医生提供最终诊断方面,组织病理学和细胞病理学通常比临床化学和微生物学更有效。它们不依赖复杂精密的设备,所需的少量试剂可无限期储存。福尔马林固定允许使用大多数组织学方法,包括特殊染色和免疫组织化学。福尔马林固定的材料在切除几天后即可检查。在热带国家建立病理实验室可能是在区域或地区层面规划诊断服务的一种切实可行且具有成本效益的方法。发展中国家的一部分医学毕业生应致力于这些实验室的人员配备。