Suppr超能文献

经常饮用绿茶可改善高血压患者的脉压并促使左心室肥厚消退。

Regular consumption of green tea improves pulse pressure and induces regression of left ventricular hypertrophy in hypertensive patients.

作者信息

Al-Shafei Ahmad I M, El-Gendy Ola A A

机构信息

Istanbul Medipol University, Istanbul, Turkey.

Bahrain University, Southern Governorate, Bahrain.

出版信息

Physiol Rep. 2019 Mar;7(6):e14030. doi: 10.14814/phy2.14030.

Abstract

This study characterized the effects of regular green tea (GT) and hot water (HW) ingestion on systolic blood pressure (SBP), diastolic blood pressure (DBP), pulse pressure (PP), and left ventricular hypertrophy (LVH) in two equal, sex- and age-matched groups; Grp1 and Grp2 (n = 100 each; age 53 ± 4 years) of hypertensive patients. Grp1 had regular GT treatment, followed by HW ingestion, whereas Grp2 had HW ingestion followed by GT treatment for periods of 4 months each. Electrocardiographic (ECG) and echocardiographic assessments of LVH were made before and at the end of both periods. SBP was lowered significantly by 6.6%; DBP by 5.1%, and PP by 9.1% by the end of month 4 of GT treatment in Grp1. Upon GT cessation and HW ingestion, SBP, DBP, and PP returned to pretreatment levels over 4 months. In Grp2, SBP, DBP, and PP were reduced insignificantly by 1.5%, 1.0%, and 2.3% by the end of the 4th month of HW ingestion. Conversely, over 4 months of GT treatment, SBP, DBP, and PP were significantly lowered by 5.4%, 4.1%, and 7.7% from the baseline values, respectively. ECG and echocardiographic evidence of LVH was shown in 20% of Grp1 and 24% of Grp2 patients before intervention. This was significantly lowered to 8% and 10% in Grp1 and Grp2 by GT treatment. However, this increased to 16% following HW ingestion in Grp1. HW ingestion did mot induce regression of LVH in Grp2. Thus, regular GT ingestion has cardiovascular protective effects.

摘要

本研究对两组年龄和性别匹配的高血压患者(每组n = 100;年龄53±4岁)进行了特征分析,这两组分别为第1组(Grp1)和第2组,研究了定期饮用绿茶(GT)和热水(HW)对收缩压(SBP)、舒张压(DBP)、脉压(PP)和左心室肥厚(LVH)的影响。第1组先进行定期GT治疗,随后饮用HW;而第2组先饮用HW,随后进行GT治疗,各为期4个月。在两个阶段开始前和结束时,对LVH进行心电图(ECG)和超声心动图评估。在第1组中,GT治疗4个月末时,SBP显著降低了6.6%;DBP降低了5.1%,PP降低了9.1%。在停止GT并饮用HW后,SBP、DBP和PP在4个月内恢复到治疗前水平。在第2组中,饮用HW 4个月末时,SBP、DBP和PP分别无显著降低,降低幅度为1.5%、1.0%和2.3%。相反,在进行4个月的GT治疗后,SBP、DBP和PP分别较基线值显著降低了5.4%、4.1%和7.7%。干预前,第1组20%的患者和第2组24%的患者有LVH的ECG和超声心动图证据。经GT治疗后,第1组和第2组的这一比例显著降至8%和10%。然而,在第1组中,饮用HW后这一比例升至16%。饮用HW未使第2组的LVH消退。因此,定期饮用GT具有心血管保护作用。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验