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茶在管理心血管危险因素中的作用:潜在益处、机制及干预策略。

The role of tea in managing cardiovascular risk factors: potential benefits, mechanisms, and interventional strategies.

作者信息

Xu Ziming, Tao Zhu, Guo Yan

机构信息

Xiyuan Hospital Affiliated to China Academy of Chinese Medical Sciences, Beijing, China.

The Chinese Journal of Integrated Traditional and Western Medicine Press, Beijing, China.

出版信息

Front Nutr. 2025 Apr 24;12:1530012. doi: 10.3389/fnut.2025.1530012. eCollection 2025.

Abstract

Traditional major cardiovascular disease (CVD) risk factors include dyslipidemia, hypertension, smoking, diabetes, and obesity. Tea is rich in various bioactive substances such as tea polyphenols, theaflavins, and tea polysaccharides. Due to the regulatory effects on multiple pathways and its anti-inflammatory and antioxidant properties, these active substances have shown significant efficacy in regulating dyslipidemia, hypertension, diabetes, obesity, and cardiac autonomic function. Additionally, tea possesses anti-inflammatory and antithrombotic properties, making it a promising dietary supplement for nutritional interventions in the primary and secondary prevention of CVDs. However, the complex composition of tea, although shown to have certain effects , does not fully elucidate the specific mechanisms of action. Moreover, the varying application methods across different studies lead to differences in intervention effects and dose-response relationships, sometimes resulting in contradictory findings. This article reviews the potential benefits, mechanisms of action, and application methods of tea for cardiovascular risk factors, elucidating its potential as a nutritional intervention.

摘要

传统的主要心血管疾病(CVD)风险因素包括血脂异常、高血压、吸烟、糖尿病和肥胖。茶富含多种生物活性物质,如茶多酚、茶黄素和茶多糖。由于这些活性物质对多种途径具有调节作用,且具有抗炎和抗氧化特性,它们在调节血脂异常、高血压、糖尿病、肥胖和心脏自主神经功能方面已显示出显著疗效。此外,茶具有抗炎和抗血栓形成特性,使其成为心血管疾病一级和二级预防营养干预中有前景的膳食补充剂。然而,茶的成分复杂,尽管已显示有一定作用,但并未完全阐明其具体作用机制。此外,不同研究中的应用方法各异,导致干预效果和剂量反应关系存在差异,有时会得出相互矛盾的结果。本文综述了茶对心血管风险因素的潜在益处、作用机制和应用方法,阐明其作为营养干预的潜力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1c5b/12058793/bd7f8cd6368e/fnut-12-1530012-g001.jpg

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