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东南亚国家与二手烟相关癌症的发病率和死亡率

Incidence and Mortality of Cancers Related to Secondhand Smoking in Southeast Asia Countries.

作者信息

Kristina Susi Ari, Permitasari Ni Putu Ayu Linda, Krisnadewi Kadek Ida, Santosa Karina Anindita

机构信息

Department of Pharmaceutics, Faculty of Pharmacy, University Gadjah Mada, Indonesia. Email:

Undergraduate Student, Faculty of Pharmacy, University Gadjah Mada, Indonesia.

出版信息

Asian Pac J Cancer Prev. 2019 Mar 26;20(3):971-976. doi: 10.31557/APJCP.2019.20.3.971.

Abstract

Background: Secondhand smoke has been a big problem for human being worldwide as it is well-established risk factors for cancers. ASEAN (Association of Southeast Asian Nations) bear high burden of cancers since the high prevalence of secondhand smoke. The objective of this study is to estimate the burden of cancer attributable to secondhand smoking in ASEAN. Methods: This research was using descriptive epidemiological incidence and prevalence-based research design, with cancers incidence and mortality data gained from GLOBOCAN 2012. Secondhand smoke attributable fractions (SAFs) of six cancers (lung, bladder, colorectal, stomach, pancreas and larynx) were estimated and burden of cancers caused by secondhand smoking in ASEAN were calculated in term of incidence and mortality. Results: Secondhand smoking estimated for 453,562 cancer cases and 323,284 of total cancer mortality in 2012. The number of incidence and death of lung cancer attributable to secondhand smoking show the highest number compared with other type of cancers. Furthermore, we found that the number of cancer cases and cancer deaths attributable to secondhand smoking varied by each countries due to differences in size of population, various background risk of the cancer, and prevalence of secondhand smoking in each country. Conclusion: Secondhand smoking has been a risk factor for about two-fifth of cancer incidence and mortality in ASEAN. Therefore, ASEAN member countries are strongly encouraged to put in place stronger tobacco control policies and to strengthen the existing tobacco control measure in order to decrease the number of secondhand smokers and more effectively control cancers.

摘要

背景

二手烟一直是全球人类面临的重大问题,因为它是公认的癌症风险因素。由于二手烟的高流行率,东盟(东南亚国家联盟)承受着很高的癌症负担。本研究的目的是估计东盟地区因二手烟导致的癌症负担。方法:本研究采用基于描述性流行病学发病率和患病率的研究设计,癌症发病率和死亡率数据来自全球癌症数据库2012。估计了六种癌症(肺癌、膀胱癌、结直肠癌、胃癌、胰腺癌和喉癌)的二手烟归因分数(SAF),并根据发病率和死亡率计算了东盟地区因二手烟导致的癌症负担。结果:2012年,二手烟估计导致453,562例癌症病例和323,284例癌症死亡。与其他类型癌症相比,因二手烟导致的肺癌发病率和死亡人数最高。此外,我们发现,由于各国人口规模、癌症背景风险以及二手烟流行率的差异,因二手烟导致的癌症病例数和癌症死亡数在各国有所不同。结论:二手烟已成为东盟地区约五分之二癌症发病率和死亡率的风险因素。因此,强烈鼓励东盟成员国制定更强有力的烟草控制政策,并加强现有的烟草控制措施,以减少二手烟吸烟者数量,更有效地控制癌症。

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