Kawabe Yusuke, Inoue Akira, Kagawa Yoshinori, Nishizawa Yujiro, Ozato Yuki, Hayashi Nobutaka, Shindo Miki, Suzuki Ken, Komatsu Hisateru, Hirota Masashi, Miyazaki Yasuhiro, Tomokuni Akira, Motoori Masaaki, Iwase Kazuhiro, Fujitani Kazumasa
Dept. of Gastrointestinal Surgery, Osaka General Medical Center.
Gan To Kagaku Ryoho. 2023 Dec;50(13):1768-1770.
We report a case of locally advanced rectal cancer that could not be curatively resected, in which the patient underwent conversion surgery after chemotherapy. The patient is a 70-year-old woman. She came to our hospital with a chief complaint of lower abdominal pain, and a close examination revealed rectal cancer with invasion of the external iliac artery and pelvic wall. She was treated with mFOLFOX6 plus cetuximab for locally advanced rectal cancer that was not amenable to surgical resection. After 11 courses of chemotherapy, significant shrinkage of the tumor was observed, and robot assisted laparoscopic high-anterior resection was performed. The patient didn't relapse at 12 months after surgery without adjuvant chemotherapy.
我们报告一例无法进行根治性切除的局部晚期直肠癌病例，该患者在化疗后接受了转化手术。患者为一名70岁女性。她因下腹部疼痛为主诉前来我院，详细检查发现直肠癌侵犯髂外动脉和盆腔壁。她接受了mFOLFOX6联合西妥昔单抗治疗无法手术切除的局部晚期直肠癌。经过11个疗程的化疗后，观察到肿瘤明显缩小，随后进行了机器人辅助腹腔镜高位前切除术。患者术后12个月未复发，未接受辅助化疗。
