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Sleep Apnea Heterogeneity, Phenotypes, and Cardiovascular Risk. Implications for Trial Design and Precision Sleep Medicine.

作者信息

Zinchuk Andrey, Yaggi H Klar

机构信息

1Department of Internal MedicineYale School of MedicineNew Haven, Connecticut.

出版信息

Am J Respir Crit Care Med. 2019 Aug 15;200(4):412-413. doi: 10.1164/rccm.201903-0545ED.

DOI:10.1164/rccm.201903-0545ED
PMID:30916985
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6701039/
Abstract
摘要

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2
The hypoxic burden of sleep apnoea predicts cardiovascular disease-related mortality: the Osteoporotic Fractures in Men Study and the Sleep Heart Health Study.睡眠呼吸暂停的低氧负荷可预测心血管疾病相关死亡率:男性骨质疏松性骨折研究和睡眠心脏健康研究。
Eur Heart J. 2019 Apr 7;40(14):1149-1157. doi: 10.1093/eurheartj/ehy624.
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Identifying obstructive sleep apnoea patients responsive to supplemental oxygen therapy.识别对补充氧疗有反应的阻塞性睡眠呼吸暂停患者。
Eur Respir J. 2018 Sep 27;52(3). doi: 10.1183/13993003.00674-2018. Print 2018 Sep.
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Prevalence, Associated Clinical Features, and Impact on Continuous Positive Airway Pressure Use of a Low Respiratory Arousal Threshold Among Male United States Veterans With Obstructive Sleep Apnea.美国男性阻塞性睡眠呼吸暂停患者中低呼吸觉醒阈值的患病率、相关临床特征及其对持续气道正压通气使用的影响。
J Clin Sleep Med. 2018 May 15;14(5):809-817. doi: 10.5664/jcsm.7112.
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Recognizable clinical subtypes of obstructive sleep apnea across international sleep centers: a cluster analysis.在国际睡眠中心中可识别的阻塞性睡眠呼吸暂停临床亚型:聚类分析。
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Thorax. 2018 May;73(5):472-480. doi: 10.1136/thoraxjnl-2017-210431. Epub 2017 Sep 21.
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Phenotypes in obstructive sleep apnea: A definition, examples and evolution of approaches.阻塞性睡眠呼吸暂停的表型:定义、示例及方法的演变。
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N Engl J Med. 2016 Sep 8;375(10):919-31. doi: 10.1056/NEJMoa1606599. Epub 2016 Aug 28.