Yasuda K, Hayashi M, Takeda N, Goshima E, Miura K
Jpn J Med. 1986 May;25(2):171-4. doi: 10.2169/internalmedicine1962.25.171.
Nonclostridial gas gangrene in diabetics results in poor prognosis. In this paper, a survived case of diabetic nonclostridial gas gangrene caused by Proteus vulgaris and Streptococcus faecalis is described and microbiological findings of 31 cases of the literatures including our own case were reviewed. Twenty of 31 cases died (64.5%). The microbiological findings in 30 cases revealed an average of 1.8 organism per case. Predominant aerobes were E. Coli (56.7%), Streptococcus faecalis (16.7%), aerobic Streptococcus and Proteus (both 13.3%) in that order. Anaerobes were found in 12 of 20 cases and isolated anaerobes were Bacteroides (8 cases) and Peptococcus (4 cases). The role of specific bacteria in causing severe form of nonclostridial gas gangrene in diabetics was suggested.
糖尿病患者发生非梭菌性气性坏疽预后较差。本文描述了1例由普通变形杆菌和粪链球菌引起的糖尿病非梭菌性气性坏疽存活病例,并复习了包括我们自己病例在内的31例文献的微生物学研究结果。31例中有20例死亡(64.5%)。30例的微生物学研究结果显示,平均每例有1.8种微生物。主要需氧菌依次为大肠杆菌(56.7%)、粪链球菌(16.7%)、需氧链球菌和变形杆菌(均为13.3%)。20例中有12例发现厌氧菌,分离出的厌氧菌为拟杆菌(8例)和消化球菌(4例)。提示了特定细菌在糖尿病患者严重非梭菌性气性坏疽发病中的作用。