Tanaka S, Fujii S, Ohashi M, Yamamoto M, Seki J, Wada M
Jpn J Med. 1983 Jan;22(1):40-4. doi: 10.2169/internalmedicine1962.22.40.
A 56-year old diabetic patient of over 20 years duration was admitted with gangrene of right foot. About a month prior to admission he injured the fourth toe of the right leg when he cut the toe nail. Two weeks later necrotic ulcer was present on it with cellulitis and 2nd, 3rd and 5th toes were also affected. Then his entire right leg was swollen and he developed fever. In spite of the treatment with antibiotics and insulin, gangrenous lesions progressed and subcutaneous emphysema was palpable beneath the inflamed area. On the 9th hospital day amputation was carried out below the knee. He had a good recovery 6 weeks after the amputation. Aerobic and anerobic cultures from the foot yielded bacteroides and pseudomonas aeruginosa. Clostridia were not isolated. A review was also carried out on ten diabetic cases of nonclostridial gas gangrene in the lower limb in Japan.
一名患糖尿病20多年的56岁患者因右足坏疽入院。入院前约一个月,他剪趾甲时伤到了右腿的第四趾。两周后,该趾出现坏死性溃疡并伴有蜂窝织炎,第二、三、五趾也受到影响。随后他的整个右腿肿胀并发热。尽管使用了抗生素和胰岛素治疗,但坏疽病变仍在进展,炎症区域下方可触及皮下气肿。入院第9天,在膝关节以下进行了截肢手术。截肢6周后他恢复良好。足部的需氧和厌氧培养均检出拟杆菌和铜绿假单胞菌,未分离出梭状芽孢杆菌。还对日本10例下肢非梭状芽孢杆菌性气性坏疽的糖尿病病例进行了回顾。