University of Pisa, Department of Clinical and Experimental Medicine, Paediatric Unit, Pisa, Italy.
University of Pisa, Department of Surgical, Medical and Molecular Pathology and Critical Care, Dental Clinic, Pisa, Italy.
Eur J Paediatr Dent. 2019 Mar;20(1):48-52. doi: 10.23804/ejpd.2019.20.01.10.
The purpose of this review was to evaluate allergic manifestations to dental local anaesthetic (LA) in children and to propose an algorithm for the diagnosis of LA allergy, in order to minimise the number of children who are wrongly categorised as allergic.
A comprehensive literature survey was performed on LA allergy in children before a dental treatment. In proposing a diagnostic algorithm, evidences from literature have been integrated with personal experience.
Data from literature showed that overall less than 1% of young patients tested for suspected LA have a positive subcutaneous test and have a positive diagnosis. A complete diagnostic procedure should include: clinical history reported by patients, objective medical records, results of skin tests and provocation test with the suspected drug. Patients with negative skin tests should perform a subcutaneous challenge, while patients with a positive skin test should be tested for a different unrelated LA.
Allergy to LA is a rare condition. A complete diagnostic algorithm will allow to identify paediatric patients correctly.
本综述旨在评估儿童对牙科局部麻醉(LA)的过敏表现,并提出 LA 过敏的诊断算法,以尽量减少将儿童错误归类为过敏的人数。
在儿童进行牙科治疗前,对 LA 过敏进行了全面的文献调查。在提出诊断算法时,文献中的证据与个人经验相结合。
文献数据显示,接受疑似 LA 检测的年轻患者中,总体上不到 1%的患者皮试阳性且诊断阳性。完整的诊断程序应包括:患者报告的临床病史、客观病历、皮肤试验结果和可疑药物的激发试验。皮试阴性的患者应进行皮下挑战,而皮试阳性的患者应测试不同的非相关 LA。
LA 过敏是一种罕见的情况。完整的诊断算法将有助于正确识别儿科患者。