Haag Stephanie L, Bernards Matthew T
Department of Chemical & Materials Engineering, University of Idaho, Moscow, ID 83843, USA.
Gels. 2017 Nov 4;3(4):41. doi: 10.3390/gels3040041.
Polyampholytes are a class of polymers made up of positively and negatively charged monomer subunits. Polyampholytes offer a unique tunable set of properties driven by the interactions between the charged monomer subunits. Some tunable properties of polyampholytes include mechanical properties, nonfouling characteristics, swelling due to changes in pH or salt concentration, and drug delivery capability. These characteristics lend themselves to multiple biomedical applications, and this review paper will summarize applications of polyampholyte polymers demonstrated over the last five years in tissue engineering, cryopreservation and drug delivery.
聚两性电解质是一类由带正电荷和负电荷的单体亚基组成的聚合物。聚两性电解质具有一系列独特的可调谐特性，这些特性由带电荷的单体亚基之间的相互作用驱动。聚两性电解质的一些可调谐特性包括机械性能、抗污特性、因pH值或盐浓度变化引起的膨胀以及药物递送能力。这些特性使其适用于多种生物医学应用，本文将总结过去五年中聚两性电解质聚合物在组织工程、冷冻保存和药物递送方面的应用。
