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[热和化学因素对细菌杀灭及选定细菌酶损伤的动力学。III. 与细菌数量减少相比,消毒剂对枯草芽孢杆菌酶的损伤]

[Kinetics of germ killing and damage to selected bacterial enzymes by thermal and chemical influences. III. Damage to enzymes from Bacillus subtilis by disinfectants compared to bacterial count reduction].

作者信息

Senkpiel K, Machmerth R, Lessen R, Horn H

出版信息

Zentralbl Bakteriol Mikrobiol Hyg B Umwelthyg Krankenhaushyg Arbeitshyg Prav Med. 1986 May;182(3):289-98.

PMID:3092504
Abstract

In the present paper a trial is reported to determine the efficacy of disinfectants by common bacteriological means as well as by biochemical methods. The results are compared, and they reveal a remarkable correlation (r = -0.9476) between the velocity constants of disinfection (1/kw) and the lg 1/Ki(app). The Ki(app)-value is the inhibition constant for the competitive inhibition of the creatine kinase reaction from Bacillus subtilis by disinfectants. The practical impacts are discussed.

摘要

在本论文中,报道了一项通过常规细菌学方法以及生化方法来确定消毒剂功效的试验。对结果进行了比较,结果显示消毒速度常数(1/kw)与lg 1/Ki(app)之间存在显著相关性(r = -0.9476)。Ki(app)值是消毒剂对枯草芽孢杆菌肌酸激酶反应竞争性抑制的抑制常数。文中还讨论了实际影响。

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