Cokkinos D V, Mallios C, Philias N, Vorides E M
Acta Cardiol. 1978;33(3):167-84.
Seven cases of an unusual type of ventricular arrhythmia, already named "Torsades de pointe" by French authors, are presented. It is characterized by a changing pattern of the ventricular complexes, spontaneous onset and cessation, and refractoriness to defibrillation and antiarrhythmic drugs which decrease intraventricular conduction. Prior to its onset, Q-T prolongation is almost universally seen in the ECG. Hypokalemia, myocardial depressants and bradycardia are common causes. Isoproterenol and rapid cardiac pacing are recommended as the treatment of choice. This arrhythmia is a distinct entity, quite different from typical ventricular tachycardia or fibrillation.
本文报告了7例特殊类型的室性心律失常，法国学者已将其命名为“尖端扭转型室速”。其特征为心室复合波形态多变、自发发作与终止，对除颤及减慢室内传导的抗心律失常药物无效。发作前，心电图几乎普遍可见QT间期延长。低钾血症、心肌抑制药及心动过缓是常见病因。推荐使用异丙肾上腺素及快速心脏起搏作为首选治疗方法。这种心律失常是一种独特的病症，与典型的室性心动过速或颤动截然不同。
