Cook W O, Richard J L, Osweiler G D, Trampel D W
Am J Vet Res. 1986 Aug;47(8):1817-25.
Effects of aflatoxin on bovine rumen motility were determined by radiotelemetric techniques. Aflatoxin altered amplitude and/or frequency of rumen contractions in steers given dosages of 0.2, 0.4, 0.6, or 0.8 mg of aflatoxin/kg of body weight. Effects of aflatoxin on rumen motility were dose dependent. An increase in elimination time of aflatoxin from rumen contents was observed in steers given the aflatoxin dosages of 0.4 to 0.8 mg/kg. The increase in elimination time of this toxin facilitates diagnostic capabilities for detecting bovine aflatoxicosis by obtaining rumen contents for analysis for aflatoxin. Aflatoxin M1 was detected in rumen contents from steers at 2 hours after aflatoxin was administered. Thus, intraruminal metabolism of aflatoxin B1 to M1 may occur.
采用无线电遥测技术测定了黄曲霉毒素对牛瘤胃运动的影响。给体重每千克分别投喂0.2、0.4、0.6或0.8毫克黄曲霉毒素的阉牛，黄曲霉毒素改变了瘤胃收缩的幅度和/或频率。黄曲霉毒素对瘤胃运动的影响具有剂量依赖性。在投喂0.4至0.8毫克/千克黄曲霉毒素剂量的阉牛中，观察到瘤胃内容物中黄曲霉毒素消除时间增加。这种毒素消除时间的增加有助于通过获取瘤胃内容物进行黄曲霉毒素分析来提高检测牛黄曲霉毒素中毒的诊断能力。在投喂黄曲霉毒素2小时后，在阉牛的瘤胃内容物中检测到黄曲霉毒素M1。因此，黄曲霉毒素B1可能在瘤胃内代谢为M1。
