[雌激素及其受体与乙型肝炎病毒相关肝细胞癌]
[Estrogen and its receptors in hepatitis B virus-related hepatocellular carcinoma].
作者信息
Yang S T, Han J Q, Wang Y D, Shen C, Zhao C Y
机构信息
Department of Infectious Diseases, the Third Affiliated Hospital of Hebei Medical University, Shijiazhuang 050051, China.
Department of Hepatopathy, PLA Army General Hospital, Beijing 100700, China.
出版信息
Zhonghua Gan Zang Bing Za Zhi. 2019 Mar 20;27(3):232-235. doi: 10.3760/cma.j.issn.1007-3418.2019.03.014.
Hepatitis B virus (HBV) infection is the most common cause of hepatocellular carcinoma in China. Epidemiological surveys show that male have a much higher incidence of hepatocellular carcinoma than female. Studies have shown that estrogen and its receptors are associated to gender disparity in hepatocellular carcinoma, but the underlying molecular mechanisms has not yet been fully elucidated. This article reviews the possible mechanisms of estrogen and its receptors in the occurrence and progression of hepatitis B virus-related hepatocellular carcinoma.
乙型肝炎病毒（HBV）感染是中国肝细胞癌最常见的病因。流行病学调查显示，男性肝细胞癌的发病率远高于女性。研究表明，雌激素及其受体与肝细胞癌的性别差异有关，但其潜在的分子机制尚未完全阐明。本文综述了雌激素及其受体在乙型肝炎病毒相关肝细胞癌发生发展中的可能机制。
Zotero 插件