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蛋白激酶C可能参与佛波酯、血小板衍生生长因子和A23187对瑞士3T3细胞中氨基酸转运的刺激作用。

Possible involvement of protein kinase C in the stimulation of amino acid transport by phorbol ester, platelet-derived growth factor and A23187 in Swiss 3T3 cells.

作者信息

Kitagawa K, Nishino H, Iwashima A

出版信息

Experientia. 1986 Sep 15;42(9):1038-40. doi: 10.1007/BF01940722.

Abstract

Stimulation of amino acid transport induced by phorbol-12,13-dibutyrate, platelet-derived growth factor or A23187 was not observed in cells lacking protein kinase C. On the other hand, stimulation of transport by epidermal growth factor or insulin was not affected. These results suggested that the stimulation of amino acid transport is mediated by at least two separate pathways.

摘要

在缺乏蛋白激酶C的细胞中,未观察到佛波醇-12,13-二丁酸酯、血小板衍生生长因子或A23187诱导的氨基酸转运刺激。另一方面,表皮生长因子或胰岛素对转运的刺激不受影响。这些结果表明,氨基酸转运的刺激至少由两条独立的途径介导。

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