Volzhskaia A M, Shumilova T E
Fiziol Zh SSSR Im I M Sechenova. 1986 Aug;72(8):1143-7.
In rats with artificial renal hypertension, the amount of erythrocytes in the blood was increased in 43% of cases within 2-3 months after surgery. Diverse changes of the blood oxygen-transport properties indicate several mechanisms of the organism adaptation to changes in oxygen regiment in response to the arterial pressure increase due to ischemia of renal tissue: an increase in the blood oxygen capacity; changes of the hemoglobin oxygen-binding properties. The parameters under study, except the arterial pressure, did not differ from the control ones in a number of experimental animals.
在人工肾性高血压大鼠中,43%的大鼠在手术后2至3个月内血液中红细胞数量增加。血液氧运输特性的多种变化表明,机体对因肾组织缺血导致动脉压升高而引起的氧供应变化存在多种适应机制:血液氧容量增加;血红蛋白氧结合特性改变。在许多实验动物中,除动脉压外,所研究的参数与对照组无差异。