世贸中心（WTC）救援人员的握力：再体验创伤后应激障碍（PTSD）症状的作用。
Handgrip Strength of World Trade Center (WTC) Responders: The Role of Re-Experiencing Posttraumatic Stress Disorder (PTSD) Symptoms.
机构信息
Community Health and Wellness, Health & Physical Education Department, Rhode Island College, Providence, RI 02908, USA.
Program in Public Health, Department of Family, Population, and Preventive Medicine, Renaissance School of Medicine at Stony Brook University, Stony Brook, NY 11794, USA.
出版信息
Int J Environ Res Public Health. 2019 Mar 29;16(7):1128. doi: 10.3390/ijerph16071128.
: This study sought to examine whether handgrip strength (HGS), a measure of muscle strength and a biomarker of aging, was associated with post-traumatic stress disorder (PTSD) in a cohort of World Trade Center (WTC) responders at midlife. : HGS was assessed utilizing a computer-assisted hand dynamometer administered to a consecutive sample of men and women ( = 2016) who participated in rescue and recovery efforts following the World Trade Center (WTC) attacks and subsequently attended monitoring appointments in Long Island, NY. PTSD symptom severity and depressive symptoms were assessed using the PTSD specific-trauma checklist (PCL-S) and the Patient Health Questionnaire (PHQ-9). General linear models were used to examine the association of WTC-related PTSD with HGS after adjusting for confounders. : The sample was at midlife (mean age = 53.3) when assessed, and 91.3% were men. Nearly 10% of the sample had probable PTSD (PCL ≥ 44) with concomitant depression (PHQ ≥ 10), while 5.1% had probable PTSD without depression. Average HGS was 57.4 lbs. (95% confidence interval (95% CI): 56.6⁻58.1) among men and 36.1 lbs. (95% CI = 33.8⁻38.5) among women. Mean HGS of those with probable PTSD with concomitant depression was lower (45.9 lbs., 95% CI = 43.6⁻48.2) than responders with only PTSD (49.1 lbs., 95% CI = 46.0⁻52.4) and those without PTSD or depression (57.5 lbs., 95% CI = 56.2⁻57.8). Subdomain analyses of PTSD symptoms revealed that re-experiencing symptoms at enrollment ( = 0.003) was associated with lower HGS after adjusting for depressive symptoms and other confounders. : Results suggested that higher WTC-related PTSD symptom severity was associated with lower HGS. Results support ongoing work suggesting that PTSD may be associated with more rapid physical aging. The potential for developing interventions that might simultaneously improve physical and mental health in the aftermath of trauma may be considered.
: 本研究旨在探讨握力（HGS）作为肌肉力量的衡量标准和衰老的生物标志物，是否与中年时期世贸中心（WTC） responder 中的创伤后应激障碍（PTSD）有关。: HGS 是通过使用计算机辅助握力计对连续的男性和女性样本（n=2016）进行评估得出的，这些人参与了世贸中心袭击事件后的救援和恢复工作，随后在纽约长岛参加了监测预约。使用 PTSD 特定创伤检查表（PCL-S）和患者健康问卷（PHQ-9）评估 PTSD 症状严重程度和抑郁症状。使用一般线性模型，在调整混杂因素后，研究 WTC 相关 PTSD 与 HGS 的关联。: 评估时，样本处于中年（平均年龄=53.3），其中 91.3%为男性。样本中近 10%患有 PTSD（PCL≥44）伴抑郁（PHQ≥10），而 5.1%患有 PTSD 无抑郁。男性平均 HGS 为 57.4 磅（95%置信区间（95%CI）：56.6⁻58.1），女性为 36.1 磅（95%CI=33.8⁻38.5）。伴有抑郁的 PTSD 可能性较高的患者的平均 HGS 较低（45.9 磅，95%CI=43.6⁻48.2），低于仅患有 PTSD（49.1 磅，95%CI=46.0⁻52.4）和无 PTSD 或抑郁的患者（57.5 磅，95%CI=56.2⁻57.8）。PTSD 症状的子域分析表明，入学时的再体验症状（=0.003）在调整抑郁症状和其他混杂因素后与较低的 HGS 相关。: 结果表明，较高的 WTC 相关 PTSD 症状严重程度与较低的 HGS 相关。结果支持正在进行的研究表明，PTSD 可能与更快的身体衰老有关。可能会考虑开发同时改善创伤后身体和心理健康的干预措施。
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