Kurita Geana Paula, Sjøgren Per, Klepstad Pål, Mercadante Sebastiano
Palliative Research Group, Department of Oncology, Rigshospitalet Copenhagen University Hospital, 2100 Copenhagen, Denmark.
Multidisciplinary Pain Centre, Department of Neuroanaesthesiology, Rigshospitalet Copenhagen University Hospital, 2100 Copenhagen, Denmark.
Cancers (Basel). 2019 Mar 29;11(4):443. doi: 10.3390/cancers11040443.
Interventional techniques to manage cancer-related pain may be efficient treatment modalities in patients unresponsive or unable to tolerate systemic opioids. However, indication and selection of the right technique demand knowledge, which is still incipient among clinicians. The present article summarizes the current evidence regarding the five most essential groups of interventional techniques to treat cancer-related pain: Neuraxial analgesia, minimally invasive procedures for vertebral pain, sympathetic blocks for abdominal cancer pain, peripheral nerve blocks, and percutaneous cordotomy. Furthermore, indication, mechanism, drug agents, contraindications, and complications of the main techniques of each group are discussed.
对于那些对全身性阿片类药物无反应或无法耐受的癌症相关疼痛患者，介入技术可能是有效的治疗方式。然而，正确技术的适应症和选择需要相关知识，而临床医生对此仍了解不足。本文总结了关于治疗癌症相关疼痛的五类最重要介入技术的现有证据：神经轴索镇痛、椎体疼痛的微创手术、腹部癌症疼痛的交感神经阻滞、周围神经阻滞和经皮脊髓切断术。此外，还讨论了每组主要技术的适应症、机制、药物、禁忌症和并发症。
