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免疫功能正常宿主的菌血症

bacteremia in an immunocompetent host.

作者信息

Butt Saira, Tirmizi Amir

机构信息

Indiana University School of Medicine, Department of Medicine, Division of Infectious Diseases, United States.

Infectious Diseases Consultant, Columbus Regional Hospital, Columbus, IN, United States.

出版信息

IDCases. 2019 Mar 12;15:e00523. doi: 10.1016/j.idcr.2019.e00523. eCollection 2019.

Abstract

Non-tuberculous mycobacteria can cause catheter associated blood stream infections. The causative agents are generally rapid growers that belong to the Mycobacterium fortuitum and Mycobacterium mucogenicum groups. A 65 year hospitalized patient with temporary central venous catheter who developed Mycobacterium smegmatis bacteremia. Bacteremia cleared after removal of the catheter. Patient was treated initially with 4 weeks of intravenous amikacin, intravenous meropenem, oral doxycycline and oral ethambutol and then deescalated to oral doxycycline and oral ciprofloxacin for 8 weeks. He improved clinically and remained stable. A literature search identified total of 22 articles that reported 47 unique cases of Mycobacterium smegmatis infection. To our knowledge, this is the first case of Mycobacterium smegmatis central venous catheter associated bacteremia in an immunocompetent host.

摘要

非结核分枝杆菌可引起导管相关血流感染。病原体通常是快速生长菌,属于偶然分枝杆菌和产黏液分枝杆菌组。一名65岁住院患者,留置临时中心静脉导管,发生耻垢分枝杆菌菌血症。拔除导管后菌血症清除。患者最初接受了4周的静脉注射阿米卡星、静脉注射美罗培南、口服多西环素和口服乙胺丁醇治疗,然后降阶梯为口服多西环素和口服环丙沙星治疗8周。他的临床症状改善并保持稳定。文献检索共发现22篇报道47例耻垢分枝杆菌感染独特病例的文章。据我们所知,这是免疫功能正常宿主中首例耻垢分枝杆菌中心静脉导管相关菌血症病例。

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