Schmidt K, Rosak C, Boehm B, Schifferdecker E, Althoff P H, Schoeffling K
Klin Wochenschr. 1986 Sep 1;64(17):804-5. doi: 10.1007/BF01732192.
A patient (19 years old) with Kallmann's syndrome was treated with gonadotropin-releasing hormone (2.5-16 micrograms) administered subcutaneously every 2 h using a portable infusion pump. During 42 weeks of treatment testosterone levels and testicular size did not increase sufficiently although no reasons for this insufficient response were detectable. Therefore the regime of controlling and changing the catheter system was intensified. By this means partial occlusions of the catheter were detected and could be corrected. Afterwards testosterone levels increased immediately and persistently to normal values.
一名患有卡尔曼综合征的19岁患者，使用便携式输液泵每2小时皮下注射促性腺激素释放激素（2.5 - 16微克）进行治疗。在42周的治疗期间，睾酮水平和睾丸大小虽未充分增加，但未发现对此反应不足的原因。因此，加强了对导管系统的控制和更换方案。通过这种方式，检测到导管存在部分堵塞并得以纠正。此后，睾酮水平立即持续上升至正常水平。
