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门诊乳腺手术中采用非阿片类药物方案的经验:阿片类药物很少有必要使用,且其使用取决于外科医生。

Experience with a Nonopioid Protocol in Ambulatory Breast Surgery: Opioids are Rarely Necessary and Use is Surgeon-Dependent.

作者信息

Rothenberg Kara A, Huyser Michelle R, Edquilang Joanne K, Cureton Elizabeth L, Kwan Rita O, Peng Peter D, Svahn Jonathan D, Shim Veronica

机构信息

Department of Surgery, University of California San Francisco-East Bay, Oakland, CA.

Department of Surgery, Kaiser Permanente, Oakland, CA.

出版信息

Perm J. 2019;23. doi: 10.7812/TPP/18-127.

DOI:10.7812/TPP/18-127
PMID:30939280
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6443369/
Abstract

CONTEXT

Surgeons write 1.8% of all prescriptions and 9.8% of all opioid prescriptions. Even small doses prescribed for short-term use can lead to abuse; thus, surgeons are uniquely able to combat the opioid epidemic by changing prescribing practices. As part of a department wide quality improvement project, we initiated a nonopioid protocol for all patients undergoing ambulatory breast surgery.

OBJECTIVE

To determine the feasibility of a nonopioid protocol for patients undergoing ambulatory breast surgery and to determine if patient-related factors contribute to surgeon adherence to a nonopioid protocol in ambulatory breast surgery.

DESIGN

Retrospective chart review of a prospectively collected database, with χ analysis and a multiple logistic regression model with the surgeon as the random effect.

MAIN OUTCOME MEASURE

Protocol adherence.

RESULTS

A total of 180 patients, with a median age of 63 years (range = 18-95 years), were included. Of these, 127 (70.6%) did not receive opioids; in this group there were 2 hematomas (1.6%), and 3 patients required an opioid prescription (2.4%). Fifty-three (29.4%) were prescribed opioids against protocol; in this group, there was 1 hematoma (1.9%). The operating surgeon was the only variable independently correlated with protocol adherence (p < 0.0001). Age, race/ethnicity, surgery type, and history of long-term opioid use were not.

CONCLUSION

Ambulatory breast surgery patients tolerated a nonopioid pain regimen well. Surgeons' decisions, rather than patient characteristics, primarily drove the choice of pain management in our study. We believe our protocol can be improved with stricter implementation and education, which must be balanced with practitioner independence.

摘要

背景

外科医生开具的处方占所有处方的1.8%,开具的阿片类药物处方占所有阿片类药物处方的9.8%。即使是短期使用的小剂量药物也可能导致滥用;因此,外科医生有独特的能力通过改变处方习惯来对抗阿片类药物流行。作为全科室质量改进项目的一部分,我们为所有接受门诊乳房手术的患者启动了一项非阿片类药物方案。

目的

确定非阿片类药物方案在门诊乳房手术患者中的可行性,并确定患者相关因素是否有助于外科医生在门诊乳房手术中遵循非阿片类药物方案。

设计

对前瞻性收集的数据库进行回顾性图表审查,采用χ分析和以外科医生为随机效应的多元逻辑回归模型。

主要观察指标

方案依从性。

结果

共纳入180例患者,中位年龄63岁(范围=18 - 95岁)。其中,127例(70.6%)未接受阿片类药物;该组有2例血肿(1.6%),3例患者需要开具阿片类药物处方(2.4%)。53例(29.4%)违反方案开具了阿片类药物;该组有1例血肿(1.9%)。手术医生是与方案依从性独立相关的唯一变量(p < 0.0001)。年龄、种族/民族、手术类型和长期使用阿片类药物史则无关。

结论

门诊乳房手术患者对非阿片类疼痛治疗方案耐受性良好。在我们的研究中,主要是外科医生的决策而非患者特征驱动了疼痛管理的选择。我们认为,通过更严格的实施和教育可以改进我们的方案,同时必须与从业者的独立性相平衡。

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本文引用的文献

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J Am Coll Surg. 2018 Aug;227(2):203-211. doi: 10.1016/j.jamcollsurg.2018.04.032. Epub 2018 May 7.
2
Changes in Provider Prescribing Patterns After Implementation of an Emergency Department Prescription Opioid Policy.实施急诊科处方阿片类药物政策后医疗服务提供者处方模式的变化
J Emerg Med. 2017 Apr;52(4):538-546. doi: 10.1016/j.jemermed.2016.07.120. Epub 2017 Jan 19.
3
Increases in Drug and Opioid-Involved Overdose Deaths - United States, 2010-2015.药物和阿片类药物滥用相关过量死亡人数增加 - 美国,2010-2015 年。
MMWR Morb Mortal Wkly Rep. 2016 Dec 30;65(50-51):1445-1452. doi: 10.15585/mmwr.mm655051e1.
4
Wide Variation and Excessive Dosage of Opioid Prescriptions for Common General Surgical Procedures.普通普外科手术中阿片类药物处方的广泛差异和过量用药
Ann Surg. 2017 Apr;265(4):709-714. doi: 10.1097/SLA.0000000000001993.
5
Opioid Induced Hyperalgesia.阿片类药物诱导的痛觉过敏。
Pain Med. 2015 Oct;16 Suppl 1:S32-6. doi: 10.1111/pme.12914.
6
Impact of an Opioid Prescribing Guideline in the Acute Care Setting.阿片类药物处方指南在急性护理环境中的影响。
J Emerg Med. 2016 Jan;50(1):21-7. doi: 10.1016/j.jemermed.2015.06.014. Epub 2015 Aug 15.
7
Trends in Opioid Analgesic-Prescribing Rates by Specialty, U.S., 2007-2012.2007 - 2012年美国按专业划分的阿片类镇痛药处方率趋势
Am J Prev Med. 2015 Sep;49(3):409-13. doi: 10.1016/j.amepre.2015.02.020. Epub 2015 Apr 18.
8
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9
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10
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Ann Surg Oncol. 2012 Nov;19(12):3792-800. doi: 10.1245/s10434-012-2447-7. Epub 2012 Jun 20.