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多模式方案减轻常见骨科运动术后疼痛:能否消除术后阿片类药物?

A Multimodal Protocol to Diminish Pain Following Common Orthopedic Sports Procedures: Can We Eliminate Postoperative Opioids?

机构信息

Division of Sports Medicine, Department of Orthopaedic Surgery, Henry Ford Hospital, Detroit, Michigan.

Tulane University Medical School, New Orleans, Louisiana.

出版信息

Arthroscopy. 2020 Aug;36(8):2249-2257. doi: 10.1016/j.arthro.2020.04.018. Epub 2020 Apr 28.

Abstract

PURPOSE

To determine whether postsurgical pain, measured by the visual analog scale (VAS), following common orthopaedic sports procedures could be managed effectively with a nonopioid multimodal analgesic protocol.

METHODS

This prospective study evaluated a custom multimodal nonopioid pain protocol in patients undergoing common orthopaedic sports procedures by a single fellowship-trained orthopaedic sports surgeon from May 2018 to December 2018. Procedures included anterior cruciate ligament reconstruction, rotator cuff repair, arthroscopic partial meniscectomy, and labrum repair. The nonopioid pain protocol consisted of preoperative analgesics, intraoperative local infiltration analgesia, and a postoperative pain regimen. Patient pain was immediately reported after surgery and 1 week postoperatively using the VAS, whereas rescue opioids (oxycodone 5 mg) used were recorded using a prescription opioid journal. Statistical analysis of patient VAS scores, demographic correlations, and comparison between opioid rescue users versus nonusers was performed.

RESULTS

A total of 141 patients were included. One week following surgery, patients reported a mean VAS level of 3.2 ± 2.3 and required on average 2.6 ± 3.6 breakthrough oxycodone pills (8.6 ± 12.0 morphine equivalents). Forty-five percent of patients did not require any breakthrough prescription opioids and reported satisfaction with pain management. Patients who required opioids were more likely to have a history of anxiety/depression (44.2% vs 23.8%, P = .012) and reported greater pain scores as compared with nonusers (3.94 ± 2.5 vs 2.41 ± 1.75, P = .016). The most common side effect of the pain protocol was feeling drowsy (23.5%). All patients were satisfied with their pain management postoperatively.

CONCLUSIONS

A multimodal, nonopioid pain protocol was found to be effective in managing postoperative pain following common orthopedic sports procedures. Patients were found to have low levels of pain, require minimal rescue opioids, and had no severe side effects related to the protocol. These results suggest a nonopioid alternative to pain management following common orthopedic sports procedures.

LEVEL OF EVIDENCE

Level IV, prospective case series.

摘要

目的

通过视觉模拟评分(VAS)来确定在接受常见骨科运动手术后,术后疼痛是否可以通过非阿片类多模式镇痛方案有效控制。

方法

这项前瞻性研究由一名经过专业培训的骨科运动外科医生于 2018 年 5 月至 2018 年 12 月期间对接受常见骨科运动手术的患者进行了评估,评估了一种定制的多模式非阿片类镇痛方案。手术包括前交叉韧带重建、肩袖修复、关节镜下半月板部分切除术和盂唇修复。非阿片类镇痛方案包括术前镇痛、术中局部浸润镇痛和术后镇痛方案。术后立即使用 VAS 评估患者的疼痛,并在术后 1 周时进行评估,同时使用处方阿片类药物日记记录使用的阿片类药物。对患者 VAS 评分、人口统计学相关性和阿片类药物解救使用者与非使用者之间的比较进行了统计学分析。

结果

共纳入 141 例患者。术后 1 周时,患者报告的平均 VAS 评分为 3.2 ± 2.3,平均需要 2.6 ± 3.6 片奥施康定(8.6 ± 12.0 吗啡当量)。45%的患者不需要任何阿片类药物补救,对疼痛管理表示满意。需要阿片类药物的患者更有可能有焦虑/抑郁病史(44.2%比 23.8%,P =.012),且与非使用者相比报告的疼痛评分更高(3.94 ± 2.5 比 2.41 ± 1.75,P =.016)。疼痛方案最常见的副作用是嗜睡(23.5%)。所有患者对术后疼痛管理均表示满意。

结论

多模式非阿片类镇痛方案被发现可有效控制常见骨科运动手术后的术后疼痛。患者的疼痛程度较低,需要的阿片类药物解救较少,且与方案相关的严重副作用发生率较低。这些结果表明,在接受常见骨科运动手术后,非阿片类药物是一种替代疼痛管理的方法。

证据水平

IV 级,前瞻性病例系列研究。

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