Amiri Sohrab, Behnezhad Sepideh
Urmia University, Urmia, Iran.
Department of Psychology, Kharazmi University, Tehran, Iran.
Int J Psychiatry Med. 2019 Apr 2:91217419837407. doi: 10.1177/0091217419837407.
Although some studies have been conducted on the association between diabetes and anxiety symptoms, the data on this association remain controversial. The purpose of this meta-analysis was to examine the association between diabetes and anxiety symptoms. The authors systematically searched PubMed, Scopus, and Google Scholar databases until July 2018. After the screening process, 23 studies were included in the meta-analysis. Stata-14 was used for meta-analyzing. Forest plot was calculated for the whole 23 studies and subgroups, and publication bias was also examined. Overall, diabetes was positively associated with anxiety; pooled odds ratio was equal to1.48; 95% confidence interval was 1 .27-1.74. In cross-sectional study, the result was odds ratio = 1.50; 95% confidence interval = 1.26-1.77, and in prospective-cohort study, the result was odds ratio = 1.34; 95% confidence interval = 1.21-1.49. There was small evidence of publication bias. Overall, our findings indicate that diabetes is a risk factor for anxiety symptoms. Therefore, having a healthy medical condition can be an anxiety prevention agent.
尽管已经有一些关于糖尿病与焦虑症状之间关联的研究，但关于这种关联的数据仍存在争议。本荟萃分析的目的是研究糖尿病与焦虑症状之间的关联。作者系统检索了截至2018年7月的PubMed、Scopus和谷歌学术数据库。经过筛选过程，23项研究被纳入荟萃分析。使用Stata-14进行荟萃分析。计算了全部23项研究及亚组的森林图，并检查了发表偏倚。总体而言，糖尿病与焦虑呈正相关；合并比值比等于1.48；95%置信区间为1.27 - 1.74。在横断面研究中，结果为比值比 = 1.50；95%置信区间 = 1.26 - 1.77，在前瞻性队列研究中，结果为比值比 = 1.34；95%置信区间 = 1.21 - 1.49。有少量发表偏倚的证据。总体而言，我们的研究结果表明糖尿病是焦虑症状的一个危险因素。因此，保持健康的身体状况可能是预防焦虑的一个因素。
