Lee MinJae, Conroy Joseph H, Yang Zihan, Lee Sein, Yeh Paul G, Lopez Juliana Z, Heredia Natalia I, Mitchell-Bennett Lisa A, Sifuentes Maribel, Reininger Belinda M
The University of Texas Health Science Center at Houston, USA.
The University of Texas Health Science Center at Houston, Brownsville, USA.
J Prim Care Community Health. 2025 Jan-Dec;16:21501319251358631. doi: 10.1177/21501319251358631. Epub 2025 Jul 30.
Adults with type 2 diabetes mellitus and comorbid depression face complex disease management. Salud y Vida, a diabetes management intervention for Mexican Americans in the Rio Grande Valley of Texas, may mitigate depression through social support and community-clinic referrals.
In a cohort study, 292 Salud y Vida participants completed the patient health questionnaire (PHQ-9) at baseline, month 6, and month 12. A PHQ-9 score of ≥5 indicated mild depression and activated a mental health referral. Using SAS 9.4 with significance set at <.05, we conducted multivariable longitudinal negative binomial regression to assess changes in depression level.
The proportion of participants with a PHQ-9 ≥5 decreased from 36% at baseline to 18% in month 6 (adjusted risk ratio = 0.51, 95% CI = 0.41-0.62; < .001). Among those with clinical depression at baseline (n = 121), mean PHQ-9 scores dropped 45% by month 6 (9.60-5.28; adjusted rate ratio = 0.55; 95% CI = 0.47, 0.65, < .001) and an additional 22% by month 12 (5.28-4.10; adjusted rate ratio = 0.78; 95% CI = 0.66, 0.91; < .002).
Salud y Vida participation is correlated with significant depression symptom improvements in Mexican American adults with diabetes and comorbid depression, demonstrating that chronic care management interventions can address multiple chronic conditions.
患有2型糖尿病且合并抑郁症的成年人面临复杂的疾病管理问题。“健康与生活”(Salud y Vida)是一项针对德克萨斯州里奥格兰德河谷地区墨西哥裔美国人的糖尿病管理干预项目,可能通过社会支持和社区诊所转诊来缓解抑郁症。
在一项队列研究中,292名“健康与生活”项目参与者在基线、第6个月和第12个月完成了患者健康问卷(PHQ - 9)。PHQ - 9得分≥5表明存在轻度抑郁,并启动心理健康转诊。使用显著性设定为<0.05的SAS 9.4软件,我们进行了多变量纵向负二项回归分析,以评估抑郁水平的变化。
PHQ - 9≥5的参与者比例从基线时的36%降至第6个月时的18%(调整风险比 = 0.51,95%置信区间 = 0.41 - 0.62;<0.001)。在基线时患有临床抑郁症的参与者(n = 121)中,到第6个月时,PHQ - 9平均得分下降了45%(从9.60降至5.28;调整率比 = 0.55;95%置信区间 = 0.47, 0.65,<0.001),到第12个月时又额外下降了22%(从5.28降至4.10;调整率比 = 0.78;95%置信区间 = 0.66, 0.91;<0.002)。
参与“健康与生活”项目与患有糖尿病且合并抑郁症的墨西哥裔美国成年人的抑郁症状显著改善相关,表明慢性病护理管理干预措施可以解决多种慢性病问题。