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莫桑比克 5 岁以下儿童疟疾的求医行为和治疗方法:对 2011 年 DHS 和 2015 年 IMASIDA 数据集的二次分析。

Care-seeking behaviour and treatment practices for malaria in children under 5 years in Mozambique: a secondary analysis of 2011 DHS and 2015 IMASIDA datasets.

机构信息

Program of Endemic Diseases of Large Impact, Instituto Nacional de Saúde, Maputo, Mozambique.

Global Health and Tropical Medicine, Instituto de Higiene e Medicina Tropical, Universidade Nova de Lisboa, Lisbon, Portugal.

出版信息

Malar J. 2019 Apr 2;18(1):115. doi: 10.1186/s12936-019-2751-9.

Abstract

BACKGROUND

In Mozambique, the prevalence of malaria in children under 5 years of age is among the highest in the world, but limited data exist on determinants of care-seeking behaviour for malaria. This study aimed at determining the trends and factors associated with care-seeking behaviour for fever among children under 5 years of age and to assess the treatment practices for malaria.

METHODS

Secondary data analysis of two cross-sectional studies. Descriptive statistics were used to summarize socio-economic and demographic characteristics of participants, using data from the 2011 Demographic and Health Survey and 2015 Indicators of Immunization, Malaria and HIV/AIDS Survey. Complex sampling logistic regression model was used to identify factors associated with care-seeking behaviour, with estimated adjusted odds ratio and respective 95% confidence intervals, only for 2015 IMASIDA data.

RESULTS

A total of 10,452 and 5168 children under 5 years of age were enrolled in the 2011 DHS and 2015 IMASIDA, respectively. Care-seeking for fever in public and private sectors remained stable during this period (62.6%; 835/1432 in 2011 and 63.7%; 974/1529 in 2015). The main place where care was sought in both surveys was public hospitals (86.2%; 773/897 in 2011 and 86.7%; 844/974 in 2015). Prescription of anti-malarial drugs increased from 42.9% (385/897) in 2011 to 53.8% (524/974) in 2015. Artemether-lumefantrine was the most used anti-malarial drug for febrile children in both surveys and its use increased from 59.0% (219/373) in 2011 to 89.3% (457/512) in 2015. Data from 2015 elucidated that care-seeking was more common in children whose mothers had a secondary level of education (AOR = 2.27 [95% CI 1.15-4.49]) and among those in poorer quintile (AOR = 1.46 [95% CI 0.83-1.90]). Mothers with higher education level (AOR = 0.16 [95% CI 0.34-0.78]) were less likely to seek out care. People from Manica (AOR = 2.49 [1.03-6.01]), Sofala ([AOR = 2.91 [1.03-8.24]), Inhambane (AOR = 3.95 [1.25-12.45]), Gaza (AOR = 3.25 [1.22-8.65]) and Maputo Province (AOR = 2.65 [1.10-6.41]) were more likely to seek care than people from Maputo City.

CONCLUSION

Data from this study showed that care-seeking in Mozambique remained suboptimal. Interventions to raise the awareness for early care-seeking during episodes of fever should be urgently reinforced and intensified.

摘要

背景

在莫桑比克,5 岁以下儿童的疟疾患病率是世界上最高的之一,但关于寻求疟疾护理行为的决定因素的数据有限。本研究旨在确定 5 岁以下儿童发热寻求护理行为的趋势和相关因素,并评估疟疾的治疗实践。

方法

对两项横断面研究进行二次数据分析。使用 2011 年人口与健康调查和 2015 年免疫、疟疾和艾滋病毒/艾滋病指标调查的数据,采用描述性统计方法总结参与者的社会经济和人口统计学特征。仅对 2015 年 IMASIDA 数据使用复杂抽样逻辑回归模型确定与寻求护理行为相关的因素,估计调整后的优势比和各自的 95%置信区间。

结果

2011 年 DHS 和 2015 年 IMASIDA 分别纳入了 10452 名和 5168 名 5 岁以下儿童。在此期间,公共和私营部门对发热的护理寻求率保持稳定(62.6%;2011 年为 1432 人中的 835 人,2015 年为 1529 人中的 974 人)。在这两项调查中,寻求护理的主要地点都是公立医院(86.2%;2011 年为 897 人中的 773 人,2015 年为 974 人中的 844 人)。抗疟药物的处方率从 2011 年的 42.9%(385/897)上升到 2015 年的 53.8%(524/974)。在这两项调查中,青蒿素-本芴醇是治疗发热儿童最常用的抗疟药物,其使用率从 2011 年的 59.0%(373 人中的 219 人)上升到 2015 年的 89.3%(512 人中的 457 人)。2015 年的数据表明,母亲受过中等教育(调整后优势比(AOR)=2.27[95%置信区间(CI)1.15-4.49])和来自较贫困五分位数(AOR=1.46[95%CI 0.83-1.90])的儿童更有可能寻求护理。教育程度较高的母亲(AOR=0.16[95%CI 0.34-0.78])寻求护理的可能性较低。来自马尼卡(AOR=2.49[1.03-6.01])、索法拉(AOR=2.91[1.03-8.24])、因班巴(AOR=3.95[1.25-12.45])、加扎(AOR=3.25[1.22-8.65])和马普托省(AOR=2.65[1.10-6.41])的人比来自马普托市的人更有可能寻求护理。

结论

本研究数据表明,莫桑比克的护理寻求率仍然不理想。应紧急加强和强化提高对发热期间早期护理寻求意识的干预措施。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f755/6444821/a78706034bfc/12936_2019_2751_Fig1_HTML.jpg

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