Romay-Barja Maria, Jarrin Inma, Ncogo Policarpo, Nseng Gloria, Sagrado Maria Jose, Santana-Morales Maria A, Aparicio Pilar, Valladares Basilio, Riloha Matilde, Benito Agustin
Centro Nacional de Medicina Tropical, Instituto de Salud Carlos III, Madrid, Spain; Red de Investigación Colaborativa en Enfermedades Tropicales, RICET, Madrid, Spain.
Centro Nacional de Epidemiología, Instituto de Salud Carlos III, Madrid, Spain.
PLoS One. 2015 Aug 18;10(8):e0135887. doi: 10.1371/journal.pone.0135887. eCollection 2015.
Malaria remains a major cause of morbidity and mortality among children under five years old in Equatorial Guinea. However, little is known about the community management of malaria and treatment-seeking patterns. We aimed to assess symptoms of children with reported malaria and treatment-seeking behaviour of their caretakers in rural and urban areas in the Bata District.
A cross-sectional study was conducted in the district of Bata and 440 houses were selected from 18 rural villages and 26 urban neighbourhoods. Differences between rural and urban caregivers and children with reported malaria were assessed through the chi-squared test for independence of categorical variables and the t-Student or the non-parametric Mann-Whitney test for normally or not-normally distributed continuous variables, respectively.
Differences between rural and urban households were observed in caregiver treatment-seeking patterns. Fever was the main symptom associated with malaria in both areas. Malaria was treated first at home, particularly in rural areas. The second step was to seek treatment outside the home, mainly at hospital and Health Centre for rural households and at hospital and private clinic for urban ones. Artemether monotherapy was the antimalarial treatment prescribed most often. Households waited for more than 24 hours before seeking treatment outside and delays were longest in rural areas. The total cost of treatment was higher in urban than in rural areas in Bata.
The delays in seeking treatment, the type of malaria therapy received and the cost of treatment are the principal problems found in Bata District. Important steps for reducing malaria morbidity and mortality in this area are to provide sufficient supplies of effective antimalarial drugs and to improve malaria treatment skills in households and in both public and private sectors.
疟疾仍然是赤道几内亚五岁以下儿童发病和死亡的主要原因。然而,对于疟疾的社区管理和治疗寻求模式知之甚少。我们旨在评估巴塔区农村和城市地区报告患有疟疾的儿童的症状及其看护人的治疗寻求行为。
在巴塔区进行了一项横断面研究,从18个农村村庄和26个城市社区中选取了440户家庭。分别通过卡方检验评估分类变量的独立性,以及通过t检验或非参数曼-惠特尼检验评估连续变量是否呈正态分布,以此来评估农村和城市看护人与报告患有疟疾的儿童之间的差异。
在看护人的治疗寻求模式方面,观察到农村和城市家庭存在差异。发热是两个地区与疟疾相关的主要症状。疟疾首先在家庭中治疗,尤其是在农村地区。第二步是到家庭以外寻求治疗,农村家庭主要去医院和健康中心,城市家庭则去医院和私人诊所。蒿甲醚单一疗法是最常开具的抗疟治疗药物。家庭在到家庭以外寻求治疗之前等待超过24小时,农村地区的延误时间最长。在巴塔,城市地区的治疗总费用高于农村地区。
寻求治疗的延误、接受的疟疾治疗类型以及治疗费用是在巴塔区发现的主要问题。在该地区降低疟疾发病率和死亡率的重要措施是提供充足的有效抗疟药物供应,并提高家庭以及公共和私营部门的疟疾治疗技能。