Department of Physical Therapy, Faculty of Rehabilitation Medicine, University of Alberta, Edmonton, Alberta, Canada.
Department of Physical Therapy, University of Alabama at Birmingham, Birmingham, Alabama, USA.
BMJ Open. 2019 Apr 1;9(4):e026622. doi: 10.1136/bmjopen-2018-026622.
People with multiple sclerosis (MS) are less physically active, and more sedentary than their peers despite evidence that activity helps to manage MS-related symptoms. Traditional approaches to increasing physical activity, such as exercise programmes, can be challenging for people with MS, especially those with walking disability. Focusing on decreasing prolonged sitting, and increasing light-intensity activities may be more feasible and result in more sustainable behaviour change in persons with MS. This paper describes the rationale and development of a sedentary behaviour intervention targeting persons with MS.
The feasibility and preliminary efficacy of a sedentary behaviour intervention will be tested using a prepost intervention design in 40 adults with MS. The 22-week programme includes a 15-week intervention and a 7-week follow-up. The intervention itself is divided into two stages: Sit-Less and Move-More. The Sit-Less stage is designed to encourage participants to break up prolonged sitting bouts, while the Move-More stage promotes increasing steps per day, in addition to interrupting sitting. The intervention is delivered through individual coaching sessions between an interventionist and a participant, and an accompanying newsletter based on social cognitive theory. A Fitbit is used to monitor activity throughout the programme. Process, resource and management metrics will be recorded (eg, retention, time required for communication during the trial). Sedentary and physical activities and MS-related symptoms are measured before and after the intervention and again during follow-up. Experiences with the programme are explored through an online survey and one-on-one interviews.
The Health Research Ethics Board at the University of Alberta granted permission to conduct this study. Results will be disseminated in scientific journals and conferences, and the MS Society of Alberta. Physical therapists and kinesiologists are important stakeholders and will be targeted during dissemination.
NCT03136744.
尽管有证据表明活动有助于控制与多发性硬化症（MS）相关的症状，但多发性硬化症患者的身体活动水平低于同龄人，久坐时间也多于同龄人。增加身体活动的传统方法，如运动方案，对多发性硬化症患者，尤其是那些有行走障碍的患者来说，可能具有挑战性。关注减少长时间久坐和增加低强度活动可能更可行，并导致多发性硬化症患者更可持续的行为改变。本文介绍了针对多发性硬化症患者的久坐行为干预措施的基本原理和开发过程。
采用前后干预设计，在 40 名多发性硬化症患者中测试久坐行为干预的可行性和初步疗效。该 22 周的方案包括 15 周的干预和 7 周的随访。干预本身分为两个阶段：减少久坐和增加活动量。减少久坐阶段旨在鼓励参与者打破长时间久坐的习惯，而增加活动量阶段则促进每天增加步数，同时打断久坐。干预是通过干预者和参与者之间的个人辅导课程以及基于社会认知理论的配套通讯来进行的。在整个方案期间，使用 Fitbit 监测活动。将记录过程、资源和管理指标（例如保留率、试验期间通讯所需的时间）。在干预前后以及随访期间测量久坐和身体活动以及与多发性硬化症相关的症状。通过在线调查和一对一访谈探索参与者对该方案的体验。
阿尔伯塔大学的健康研究伦理委员会批准了进行这项研究的许可。研究结果将在科学期刊和会议上以及阿尔伯塔省多发性硬化症协会上发表。物理治疗师和运动学家是重要的利益相关者，在传播过程中会针对他们进行宣传。
NCT03136744。
