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经皮椎间孔镜下腰椎间盘摘除术的初步研究:一种治疗药物难治性神经根病和恢复脊柱功能的现代策略。

A Pilot Study of Percutaneous Interlaminar Endoscopic Lumbar Sequestrectomy: A Modern Strategy to Tackle Medically-Refractory Radiculopathies and Restore Spinal Function.

作者信息

Priola Stefano Maria, Ganau Mario, Raffa Giovanni, Scibilia Antonino, Farrash Faisal, Germanò Antonino

机构信息

Neurosurgical Clinic, Department of Neurosciences, University of Messina, Messina, Italy.

Division of Neurosurgery, Toronto Western Hospital, University of Toronto, Toronto, ON, Canada.

出版信息

Neurospine. 2019 Mar;16(1):120-129. doi: 10.14245/ns.1836210.105. Epub 2019 Mar 31.

Abstract

OBJECTIVE

Angled scopes allow 360° visualization, which makes percutaneous endoscopic techniques (percutaneous endoscopic lumbar discectomy, PELD) particularly attractive for sequestrectomies, which entail the removal of extruded lumbar disc fragments that have migrated caudally or cranially between the ligaments, foramina, and neural structures, while preserving the disc. Although many different PELD techniques are currently available, not all of them are suitable for sequestrectomies; furthermore, long-term follow-up data are unfortunately lacking.

METHODS

A pilot study was conducted on a cohort of 270 patients with lumbar radiculopathy undergoing minimally invasive spine surgery (PELD or microdiscectomy), of whom only 7 were eligible for endoscopic interlaminar sequestrectomy with disc preservation. The patients' baseline conditions and clinical outcomes were measured with the Oswestry Disability Index and a visual analogue scale. Long-term follow-up was conducted using satisfaction questionnaires that were based on the MacNab criteria and administered by medical/nursing personnel not involved in their primary surgical management.

RESULTS

EasyGo system was eventually used in 5 PELD cases. No dural tears, infections, or nerve root injuries were recorded in patients undergoing sequestrectomy. Surgical events, including blood loss and overall length of hospital stay, did not differ significantly among the 270 patients. In the group treated with endoscopic sequestrectomy, no recurrences or complications were noted during a follow-up of 3 years, and an excellent degree of satisfaction was reported.

CONCLUSION

We provide OCEBM (Oxford Centre for Evidence-Based Medicine) level 3 evidence that interlaminar endoscopic sequestrectomy is a tailored and well-tolerated surgical option; nonetheless, a cost-effectiveness analysis assessing the interval until return to working activities and long-term benefits is warranted.

摘要

目的

成角内镜可实现360°可视化,这使得经皮内镜技术(经皮内镜下腰椎间盘切除术,PELD)对于椎间盘切除术特别具有吸引力,这种手术需要切除在韧带、椎间孔和神经结构之间向尾侧或头侧移位的腰椎间盘突出碎片,同时保留椎间盘。尽管目前有许多不同的PELD技术,但并非所有技术都适用于椎间盘切除术;此外,遗憾的是缺乏长期随访数据。

方法

对270例接受微创脊柱手术(PELD或显微椎间盘切除术)的腰椎神经根病患者进行了一项前瞻性研究,其中只有7例符合内镜下椎板间椎间盘切除术并保留椎间盘的条件。使用Oswestry功能障碍指数和视觉模拟量表测量患者的基线状况和临床结果。采用基于MacNab标准的满意度问卷进行长期随访,问卷由未参与其初次手术治疗的医护人员发放。

结果

最终在5例PELD病例中使用了EasyGo系统。接受椎间盘切除术的患者未记录到硬脊膜撕裂、感染或神经根损伤。270例患者的手术相关情况,包括失血量和住院总时长,差异无统计学意义。在内镜下椎间盘切除术治疗组中,3年随访期间未发现复发或并发症,患者满意度较高。

结论

我们提供了牛津循证医学中心(OCEBM)3级证据,表明椎板间内镜下椎间盘切除术是一种针对性强且耐受性良好的手术选择;尽管如此,仍有必要进行成本效益分析,评估恢复工作活动的时间间隔和长期效益。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3dd5/6449818/dfadcda60c3e/ns-1836210-105f1.jpg

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