Ofori Emmanuel Kwaku, Owusu-Ababio Dorcas, Tagoe Emmanuel A, Asare-Anane Henry
Department of Chemical Pathology, School of Biomedical and Allied Health Sciences (S.B.A.H.S.), University of Ghana, Accra, Ghana.
Department of Medical Laboratory, Narh-Bita College, Tema, Ghana.
BMC Res Notes. 2019 Apr 3;12(1):204. doi: 10.1186/s13104-019-4245-9.
This study aimed to evaluate dyslipidemia in Ghanaian subjects with type 2 diabetes.
Hundred individuals with type 2 diabetes and 61 apparently healthy controls participated. The prevalence of hypercholesterolemia among persons with type 2 diabetes was 53%. Blood pressure, fasting blood glucose (FBG), triglyceride (TG), low-density lipoproteins (LDL) and alanine transaminase (ALT) levels were higher in persons with type 2 diabetes compared with the control group (p < 0.01). Positive correlations were found within persons with type 2 diabetes for triglyceride vs FBG; ALT vs age and aspartate transaminase (AST) vs TG (p < 0.05 respectively). This study demonstrated hyperlipidemia and poor liver health in persons with type 2 diabetes.
本研究旨在评估加纳2型糖尿病患者的血脂异常情况。
100名2型糖尿病患者和61名明显健康的对照者参与了研究。2型糖尿病患者中高胆固醇血症的患病率为53%。与对照组相比,2型糖尿病患者的血压、空腹血糖(FBG)、甘油三酯(TG)、低密度脂蛋白(LDL)和丙氨酸转氨酶(ALT)水平更高(p < 0.01)。在2型糖尿病患者中,甘油三酯与FBG、ALT与年龄、天冬氨酸转氨酶(AST)与TG之间存在正相关(p分别< 0.05)。本研究表明2型糖尿病患者存在高脂血症和肝脏健康状况不佳的情况。