Department of Community Medicine and Behavioral Sciences, Faculty of Medicine, Kuwait University, Safat, Kuwait.
Biochemistry and Molecular Biology Department, Dasman Diabetes Institute, Kuwait City, Kuwait.
J Diabetes Res. 2019 Mar 3;2019:9136250. doi: 10.1155/2019/9136250. eCollection 2019.
Gestational diabetes mellitus (GDM) is a growing global public health problem that can have short- and long-term health consequences for the mother and the child. Despite its criticalness, many countries still do not have the epidemiological data which could guide them in responding to the problem. Due to the lack of knowledge on GDM and the fact that diabetes and obesity are high in Kuwait, this study sought to estimate the prevalence of GDM and determine its risk factors and outcomes.
This cross-sectional study enrolled 947 mothers living in Kuwait, who had given birth within the previous four years. Participants were recruited from primary health care clinics and public hospitals. GDM status was self-reported by the mother. Associations between exposures and outcomes were evaluated using logistic regression, and adjusted odds ratios (aORs) and 95% confidence intervals (CIs) were estimated.
Of the 868 mothers with no prior history of diabetes mellitus, 109 (12.6%, 95% CI: 10.4, 14.8) reported having been given a GDM diagnosis during their last pregnancy. The prevalence of GDM increased with maternal age and prepregnancy body mass index. GDM was positively associated with caesarean section delivery (aOR = 1.76, 95% CI: 1.17, 2.66) and fetal macrosomia (aOR = 2.36, 95% CI: 1.14, 4.89).
GDM is prevalent in Kuwait and is associated with poor maternal, fetal, and neonatal outcomes. To date, GDM has received little attention, and there is a need for more research to identify and respond to individual and public health implications of GDM in Kuwait.
妊娠糖尿病(GDM)是一个日益严重的全球公共卫生问题,会对母亲和孩子的短期和长期健康产生影响。尽管其重要性不言而喻,但许多国家仍缺乏相关的流行病学数据,无法针对该问题采取相应的措施。由于对 GDM 的了解不足,且科威特的糖尿病和肥胖症发病率较高,本研究旨在评估 GDM 的流行率,并确定其危险因素和结局。
本横断面研究纳入了 947 名居住在科威特、且在过去四年内分娩的母亲。研究对象从初级保健诊所和公立医院招募。GDM 状态由母亲本人报告。采用逻辑回归评估暴露因素与结局之间的关联,并估计调整后的优势比(aOR)和 95%置信区间(CI)。
在 868 名无糖尿病既往史的母亲中,有 109 名(12.6%,95%CI:10.4,14.8)报告在最近一次妊娠中被诊断为 GDM。GDM 的流行率随母亲年龄和孕前体重指数的增加而升高。GDM 与剖宫产分娩(aOR=1.76,95%CI:1.17,2.66)和胎儿巨大儿(aOR=2.36,95%CI:1.14,4.89)呈正相关。
GDM 在科威特较为普遍,与不良的母婴和新生儿结局相关。迄今为止,GDM 尚未得到足够的重视,需要进一步研究以确定和应对 GDM 对科威特个人和公共卫生的影响。