Moghimi Sasan, Hou Huiyuan, Rao Harsha L, Weinreb Robert N
From the Hamilton Glaucoma Center, Shiley Eye Institute, Viterbi Family Department of Ophthalmology, University of California, San Diego, CA, United States; and Narayana Nethralaya, Bangalore, India.
Asia Pac J Ophthalmol (Phila). 2019;8(2):115-125. doi: 10.22608/APO.201914.
Optical coherence tomography angiography (OCTA) is a new modality in ocular imaging which provides non-invasive assessment and measurement of the vascular structures in the retina and optic nerve head. This technique provides useful information in glaucoma, such as quantitative assessment of vessel density. Vessel density measurement can be affected by various subject-related, eye-related, and disease-related factors. Overall, OCTA has good repeatability and reproducibility, and can differentiate glaucoma eyes from normal eyes. It can also help detect early glaucoma, reach a floor effect at a more advanced disease stage than optical coherence tomography (OCT), and adds information about glaucoma patients at risk of progression. Although it has higher variability than OCT, it also promises to be useful for monitoring glaucoma by detecting progression throughout the glaucoma continuum.
光学相干断层扫描血管造影（OCTA）是眼部成像的一种新方法，可对视网膜和视神经乳头的血管结构进行无创评估和测量。该技术在青光眼方面提供了有用信息，例如血管密度的定量评估。血管密度测量会受到各种与受试者、眼睛和疾病相关的因素影响。总体而言，OCTA具有良好的可重复性和再现性，能够区分青光眼眼和正常眼。它还可以帮助检测早期青光眼，在比光学相干断层扫描（OCT）更晚期的疾病阶段达到平台效应，并为有病情进展风险的青光眼患者增加相关信息。尽管它比OCT具有更高的变异性，但它也有望通过在整个青光眼病程中检测病情进展来监测青光眼。
