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移动筛查单位用于早期乳腺癌和心血管疾病的检测:意大利南部的一项远程医疗初步研究。

Mobile Screening Units for the Early Detection of Breast Cancer and Cardiovascular Disease: A Pilot Telemedicine Study in Southern Italy.

机构信息

Department of Environmental, Biological, and Pharmaceutical Sciences and Technologies, University of Campania "Luigi Vanvitelli," Caserta, Italy.

Department of Integrated Telemedicine Services, "Sant'Anna e San Sebastiano" Hospital, Caserta, Italy.

出版信息

Telemed J E Health. 2020 Mar;26(3):286-293. doi: 10.1089/tmj.2018.0328. Epub 2019 Apr 4.

Abstract

Telemedicine is the use of Information and Communication Technologies (ICT) to improve patient outcomes by increasing access to care, medical information and services. The aim of this pilot study was to evaluate and support the implementation of screening and early detection programs in the prevention of breast cancer and cardiovascular diseases with the establishment of a remote diagnosis through the use of ICT in mobile units. A total of 430 individuals were recruited in an area of Southern Italy. Particularly, 321 women were recruited to undergo breast cancer screening in accordance with Italian guidelines. Likewise, cardiovascular screening interested 109 subjects. A self-contained mobile unit with connectivity was provided to offer breast and cardiovascular screenings. To maximize the benefit, we have evaluated the return of investment. The telemedicine screening program allowed the detection of early pathologies. In breast cancer screening, 40.8% of cases were negative to lesions, 34.9% were positive to benign lesions, and 3.1% presented suspicious malignant lesions; these lesions were further checked by histological analyses, which showed a positive response in 70% of cases. The cardiovascular screening concerned 109 participants based on age and other risk factors. We observed a significant difference among risk factors in patients with cardiac disease (p < 0.001); particularly, hypertension was significantly the most present risk factor (51.4%, p < 0.05), followed by smoking (28.4%, p < 0.05). A cardiovascular pathology was detected in 40.4% of enrolled subjects. A 3.3:1 return on investment was calculated. Our findings demonstrate that telemedicine may represent a promising approach to deliver several health services, such as screening programs, with users who cannot utilize services in their locations. The use of telemedicine on diagnostic campers greatly reduces the costs of screening for breast cancer and major cardiovascular diseases within the Southern Italian Health Service. We believe that public investment can have a further significant return on investment by implementing the principles of precision medicine.

摘要

远程医疗是利用信息和通信技术(ICT)来改善患者的治疗效果,增加对医疗服务的可及性,获取医疗信息。本研究旨在评估和支持通过在移动单元中使用 ICT 建立远程诊断,来实施乳腺癌和心血管疾病的筛查和早期发现计划。研究在意大利南部地区招募了 430 名参与者。其中,321 名女性按照意大利指南进行乳腺癌筛查。同样,109 名受试者进行了心血管筛查。提供了一个独立的移动单元,具有连接功能,以提供乳房和心血管筛查服务。为了实现最大效益,我们评估了投资回报。远程医疗筛查计划发现了早期病变。在乳腺癌筛查中,40.8%的病例无病变,34.9%的病例良性病变,3.1%的病例疑似恶性病变;这些病变通过组织学分析进一步检查,结果显示 70%的病例呈阳性反应。心血管筛查涉及 109 名根据年龄和其他风险因素选择的参与者。我们观察到患有心脏病的患者的风险因素之间存在显著差异(p < 0.001);特别是,高血压是最常见的风险因素(51.4%,p < 0.05),其次是吸烟(28.4%,p < 0.05)。在登记的受试者中发现了 40.4%的心血管病变。投资回报率为 3.3:1。我们的研究结果表明,远程医疗可能是一种有前途的方法,可以为用户提供无法在当地使用的服务,如筛查计划。在南部意大利卫生服务中,使用远程医疗对诊断露营者进行乳腺癌和主要心血管疾病的筛查可以大大降低成本。我们认为,通过实施精准医学原则,公共投资可以获得更高的投资回报。

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